FOXM1 (NM_021953) Human Untagged Clone

CAT#: SC112825

FOXM1 (untagged)-Human forkhead box M1 (FOXM1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FOXM1
• Synonyms: FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112825 sequence for NM_021953 edited (data generated by NextGen Sequencing)
  ATGAAAACTAGCCCCCGTCGGCCACTGATTCTCAAAAGACGGAGGCTGCCCCTTCCTGTT
  CAAAATGCCCCAAGTGAAACATCAGAGGAGGAACCTAAGAGATCCCCTGCCCAACAGGAG
  TCTAATCAAGCAGAGGCCTCCAAGGAAGTGGCAGAGTCCAACTCTTGCAAGTTTCCAGCT
  GGGATCAAGATTATTAACCACCCCACCATGCCCAACACGCAAGTAGTGGCCATCCCCAAC
  AATGCTAATATTCACAGCATCATCACAGCACTGACTGCCAAGGGAAAAGAGAGTGGCAGT
  AGTGGGCCCAACAAATTCATCCTCATCAGCTGTGGGGGAGCCCCAACTCAGCCTCCAGGA
  CTCCGGCCTCAAACCCAAACCAGCTATGATGCCAAAAGGACAGAAGTGACCCTGGAGACC
  TTGGGACCAAAACCTGCAGCTAGGGATGTGAATCTTCCTAGACCACCTGGAGCCCTTTGC
  GAGCAGAAACGGGAGACCTGTGCAGATGGTGAGGCAGCAGGCTGCACTATCAACAATAGC
  CTATCCAACATCCAGTGGCTTCGAAAGATGAGTTCTGATGGACTGGGCTCCCGCAGCATC
  AAGCAAGAGATGGAGGAAAAGGAGAATTGTCACCTGGAGCAGCGACAGGTTAAGGTTGAG
  GAGCCTTCGAGACCATCAGCGTCCTGGCAGAACTCTGTGTCTGAGCGGCCACCCTACTCT
  TACATGGCCATGATACAATTCGCCATCAACAGCACTGAGAGGAAGCGCATGACTTTGAAA
  GACATCTATACGTGGATTGAGGACCACTTTCCCTACTTTAAGCACATTGCCAAGCCAGGC
  TGGAAGAACTCCATCCGCCACAACCTTTCCCTGCACGACATGTTTGTCCGGGAGACGTCT
  GCCAATGGCAAGGTCTCCTTCTGGACCATTCACCCCAGTGCCAACCGCTACTTGACATTG
  GACCAGGTGTTTAAGCCACTGGACCCAGGGTCTCCACAATTGCCCGAGCACTTGGAATCA
  CAGCAGAAACGACCGAATCCAGAGCTCCGCCGGAACATGACCATCAAAACCGAACTCCCC
  CTGGGCGCACGGCGGAAGATGAAGCCACTGCTACCACGGGTCAGCTCATACCTGGTACCT
  ATCCAGTTCCCGGTGAACCAGTCACTGGTGTTGCAGCCCTCGGTGAAGGTGCCATTGCCC
  CTGGCGGCTTCCCTCATGAGCTCAGAGCTTGCCCGCCATAGCAAGCGAGTCCGCATTGCC
  CCCAAGGTGCTGCTAGCTGAGGAGGGGATAGCTCCTCTTTCTTCTGCAGGACCAGGGAAA
  GAGGAGAAACTCCTGTTTGGAGAAGGGTTTTCTCCTTTGCTTCCAGTTCAGACTATCAAG
  GAGGAAGAAATCCAGCCTGGGGAGGAAATGCCACACTTAGCGAGACCCATCAAAGTGGAG
  AGCCCTCCCTTGGAAGAGTGGCCCTCCCCGGCCCCATCTTTCAAAGAGGAATCATCTCAC
  TCCTGGGAGGATTCGTCCCAATCTCCCACCCCAAGACCCAAGAAGTCCTACAGTGGGCTT
  AGGTCCCCAACCCGGTGTGTCTCGGAAATGCTTGTGATTCAACACAGGGAGAGGAGGGAG
  AGGAGCCGGTCTCGGAGGAAACAGCATCTACTGCCTCCCTGTGTGGATGAGCCGGAGCTG
  CTCTTCTCAGAGGGGCCCAGTACTTCCCGCTGGGCCGCAGAGCTCCCGTTCCCAGCAGAC
  TCCTCTGACCCTGCCTCCCAGCTCAGCTACTCCCAGGAAGTGGGAGGACCTTTTAAGACA
  CCCATTAAGGAAACGCTGCCCATCTCCTCCACCCCGAGCAAATCTGTCCTCCCCAGAACC
  CCTGAATCCTGGAGGCTCACGCCCCCAGCCAAAGTAGGGGGACTGGATTTCAGCCCAGTA
  CAAACCTCCCAGGGTGCCTCTGACCCCTTGCCTGACCCCCTGGGGCTGATGGATCTCAGC
  ACCACTCCCTTGCAAAGTGCTCCCCCCCTTGAATCACCGCAAAGGCTCCTCAGTTCAGAA
  CCCTTAGACCTCATCTCCGTCCCCTTTGGCAACTCTTCTCCCTCAGATATAGACGTCCCC
  AAGCCAGGCTCCCCGGAGCCACAGGTTTCTGGCCTTGCAGCCAATCGTTCTCTGACAGAA
  GGCCTGGTCCTGGACACAATGAATGACAGCCTCAGCAAGATCCTGCTGGACATCAGCTTT
  CCTGGCCTGGACGAGGACCCACTGGGCCCTGACAACATCAACTGGTCCCAGTTTATTCCT
  GAGCTACAGTAG
  
  Clone variation with respect to NM_021953.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021953 unedited
  GTGTACCATTTTGTAATACAACTCACTATAGGCGGCCGCGAAATTCGCACGAGGGGTCCA
  CACTTGTGATTCTCAATGGAGAGTGAAAACGCAGATTCATAATGAAAACTAGCCCCCGTC
  GGCCACTGATTCTCAAAAGACGGAGGCTGCCCCTTCCTGTTCAAAATGCCCCAAGTGAAA
  CATCAGAGGAGGAACCTAAGAGATCCCCTGCCCAACAGGAGTCTAATCAAGCAGAGGCCT
  CCAAGGAAGTGGCAGAGTCCAACTCTTGCAAGTTTCCAGCTGGGATCAAGATTATTAACC
  ACCCCACCATGCCCAACACGCAAGTAGTGGCCATCCCCAACAATGCTAATATTCACAGCA
  TCATCACAGCACTGACTGCCAAGGGAAAAGAGAGTGGCAGTACTGGGCCCAACAAATTCA
  TCCTCATCACCTGTGGGGGAGCCCCAACTCAGCCTCCAGGACTCCGGCCTCAAACCCAAA
  CCAGCTATGATGCCAAAAGGACAGAAGTGACCCTGGAGACCTTGGGACCAAAACCTGCAG
  CTAGGGATGTGAATCTTCCTAGACCACCTGTAGCCCTTTGCGAGCAGAAACGGGAGACCT
  GTGCAGATGGTGAGGCACCAGGCTGCACTATCAACAATAGCCTATTCCACATCCAGTGGC
  CTTCGAAAGATGAGTCCTGATGGCCTGGGCCTCCCCAGCATCAAGCCAGAGATGGAGGGA
  AAGGAAAATTTGTCACCTCGGGCACACCACAGGTTAAGGTTGAAGAGCCTTCCGAAACCT
  CATCGTCCCGGAACAACCCTGTGTCTCGACGGACACCTCACTCTTACATGGGCATGAAAC
  CAATCGCCATCAACCCCATTGATAAGAAGCCCATGCACTTTGAAAACATCTATACGTCGC
  ATTGAGGACCCTCTTCCTTACTTAACCCCTTTGCCAGCCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021953 unedited
  AATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCATGTCCACCTTCGCTTTTATTGAGTA
  GTTAGTGTTCTCAAGCTGGCTCACACCCATGCGGTCAGCTGGGGCCTAGGGTGGCTCTTT
  GCAAAGCTGAGGGGCAAGCTAAGGAAGCCAGGCAGGTCAGGGGCCCTTTCGGCCTTCTCA
  AGCCTCCACCTGAGTTCTCGTCAATGCCAGTCTCCCTGGTATGATTGGGGACATTATCAG
  AGAAACATCTAATAGCGCACATCTGGGCACCCACACTCTGCTTCAGTTGCATCCATCCTC
  CCACCCCAAATTCAACTCCTGACCCAATACAAAAGACTTTTTTAACCAGGATTTCTTCTT
  GCAGGAAAGCTGACTTGGAAACACGGGGAGGTGGCAGGGAGGGGCAAAAAGGACTCTGGC
  AAGCAGATCCACTTGTCTGGGTCCCTGCAGTGAAGAACCCAAGATCCAGGTACCTCAGCC
  TGGAAGAAACCGTGCACTGCAGGTCTTCCCTTCTATCAAAACTAAAAGCAAGGAACAGAA
  GTCAATTGAAACCCCAGGTCATCCTACCCACCTTCTGGCAGTCTCTGGATAATGATCTAA
  GGAAATAAGCTTACATTTATAATTAGAGGATAATTTGGAGAATTTATACTATTTACACGG
  ACCACNCCTGCAAGATCAGGNAAGGGTAGAGACTGCTGGGCAGAGAATGGAAACAGGCTG
  GAGGGNTCCTAATCTCTTTTACCATTGGCTTAGTAGNTCCACCCCNCAGCTTCTGGCAGG
  GACAGCAGATGAATCAGATACTCCTGGGGAACACAAAGTCCCANCAGTGGCTATGGTGTG
  ACTGCTACTTTTGCATATCCAGGCACCAAGGAGCTATGAGGAGCANAANCAGTCCTGGCC
  TGCTGCCCTCACTCAAAGGCTCGGGNTGACCTGAGCCTTGGATGCCCCGGATGTTGGCAG
  CTTGNCCAAGGGCAAGCCAGGCCTTACTGACTCAGGATAACTGGACANNTGAGTGTCAGG
  CCCAAGGGTCCTTCC
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021953
• Insert Size: 3460 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021953.2, NP_068772.2
• RefSeq Size: 3527 bp
• RefSeq ORF: 2292 bp
• Locus ID: 2305
• UniProt ID: Q08050
• Cytogenetics: 12p13.33
• Domains: FH
• Protein Families: Transcription Factors
• Gene Summary: The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.