CD8A (NM_001768) Human Untagged Clone

CAT#: SC111602

CD8A (untagged)-Human CD8a molecule (CD8A), transcript variant 1

USD 196.00


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Size
    • 10 ug

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Specifications

Product Data
Product Name CD8A (NM_001768) Human Untagged Clone
Symbol CD8A
Synonyms CD8; Leu2; MAL; p32
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC111602 sequence for NM_001768 edited (data generated by NextGen Sequencing)
ATGGCCTTACCAGTGACCGCCTTGCTCCTGCCGCTGGCCTTGCTGCTCCACGCCGCCAGG
CCGAGCCAGTTCCGGGTGTCGCCGCTGGATCGGACCTGGAACCTGGGCGAGACAGTGGAG
CTGAAGTGCCAGGTGCTGCTGTCCAACCCGACGTCGGGCTGCTCGTGGCTCTTCCAGCCG
CGCGGCGCCGCCGCCAGTCCCACCTTCCTCCTATACCTCTCCCAAAACAAGCCCAAGGCG
GCCGAGGGGCTGGACACCCAGCGGTTCTCGGGCAAGAGGTTGGGGGACACCTTCGTCCTC
ACCCTGAGCGACTTCCGCCGAGAGAACGAGGGCTACTATTTCTGCTCGGCCCTGAGCAAC
TCCATCATGTACTTCAGCCACTTCGTGCCGGTCTTCCTGCCAGCGAAGCCCACCACGACG
CCAGCGCCGCGACCACCAACACCGGCGCCCACCATCGCGTCGCAGCCCCTGTCCCTGCGC
CCAGAGGCGTGCCGGCCAGCGGCGGGGGGCGCAGTGCACACGAGGGGGCTGGACTTCGCC
TGTGATATCTACATCTGGGCGCCCTTGGCCGGGACTTGTGGGGTCCTTCTCCTGTCACTG
GTTATCACCCTTTACTGCAACCACAGGAACCGAAGACGTGTTTGCAAATGTCCCCGGCCT
GTGGTCAAATCGGGAGACAAGCCCAGCCTTTCGGCGAGATACGTCTAA

Clone variation with respect to NM_001768.6
5' Read Nucleotide Sequence
>OriGene 5' read for NM_001768 unedited
AGTATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGGCTCCCGCG
CGCCTCCCCTCGCGCCCGAGCTTCGAGCCAAGCAGCGTCCTGGGGAGCGCGTCATGGCCT
TACCAGTGACCGCCTTGCTCCTGCCGCTGGCCTTGCTGCTCCACGCCGCCAGGCCGAGCC
AGTTCCGGGTGTCGCCGCTGGATCGGACCTGGAACCTGGGCGAGACAGTGGAGCTGAAGT
GCCAGGTGCTGCTGTCCAACCCGACGTCGGGCTGCTCGTGGCTCTTCCAGCCGCGCGGCG
CCGCCGCCAGTCCCACCTTCCTCCTATACCTCTCCCAAAACAAGCCCAAGGCGGCCGAGG
GGCTGGACACCCAGCGGTTCTCGGGCAAGAGGTTGGGGGACACCTTCGTCCTCACCCTGA
GCGACTTCCGCCGAGAGAACGAGGGCTACTATTTCTGCTCGGCCCTGAGCAACTCCATCA
TGTACTTCAGCCACTTCGTGCCGGTCTTCCTGCCAGCGAAGCCCACCACGACGCCAGCGC
CGCGACCACCAACACCGGCGCCCACCATCGCGTCGCAGCCCCTGTCCCTGCGCCCAGAGG
CGTGCCGGCCAGCGGCGGGGGGCGCAGTGCACACGAAGGGGCTGGACTTCGCCTGTGATA
TCTACATCTGGGCGCCCTTGGCCGGGACTTNGTGGGTCCTTCTCCTGTCACTGGNTATCA
CCCTTTACTGNCACCACAGGNAACCCGAGACGTGTTTGCAAATGTCCCCCGGCCTGTGGT
CAAATCGGNAGACAAGCCCAGCCTTTCNGCGAGATACGTCTAACCCTGTGCACAGCCACT
ACATTACTTTCAACTGAGATCCTTCCCTTTTGAGGGGAGCAGTNCNTTCCCTTTCATTNT
TTNCCAGGCTNCCTCCTGGGNATNCATTCTCATGAATATTAT
3' Read Nucleotide Sequence
>OriGene 3' read for NM_001768 unedited
ACCGCGGCCGCATTTTANAGTCGAGTTTTTTTTTTTTTTTTTTTGCTGTTTACCCATTAA
AGAGGATGCTACAAATGTTTATTCATTAAAGCCACTCATAACAGCATAGTACAACCCTAT
TTAAAAAAGAAAGACATATTTTACATGTATGTGTAGAAAATAATCAGGAAGAATGTACAC
CATATTAACAGGAGATTATTCCTAAGGTGAAGAATTATGAGTGGTTCTTATTTCCTTATC
TACTTAAGTTTTTTCTCTCCAATGGGCAGGCATTGCTTGTACCATACCTTAAGCAAGGAA
GTGCATGTTTGGGACAGCAGTTTGGGCTCTCAGCCTCCTTAAGAGAGTCAGGTCTGCCTC
ATCCCTGTATCTGCTAGTTGAGCAGAGGCCAGGGCTGTGTGAGGGGCTCTCCAACAATTG
TCTTTACAAAGTATAAAAAGTCATCAGTGATCCCAGGAACATGTTTGTATCTCAAATTCA
GAGATTCAAGAGGGCCTTAGTTTAACCTCACTGATGCTCAAATTCTATTTGTAAAGGGGT
AGCCTGTCCTCTTTCATGGGCCCCTCTGCAATGCAAGGGCTGGGAGAGCAATTCCGCCTC
CACATAGGGGTTTCACAGAGATTTTCTTTAGAGATAGAGGGATTCATTTTCCAGGGTTAA
GCTCACCACTTCATTTTATTTTAGGTCTATACAATTNTAAGCTCGATTATTAAAAAAAAA
AGTCTGATATTGTTTACATTATAGAACTTTGCCAAAGGCAGCNCTCATTCTTTATTCATT
ACCTCCTTGAGGCTTTGGCACAGTATCCCAAGTATTAAGAAGGACTTGTTCCCTTGCCGT
TGGGACTTAAGCCCCTCACCTGAAACAGGGCCTCTGAAAGAAGCACCGAATGTGTGGAGG
AAGAACCCTGACTTGGAAGACAAGTCCCTTC
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_001768
ORF Size 708 bp
Insert Size 2210
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_001768.4, NP_001759
RefSeq Size 2261
Locus ID 925
Cytogenetics 2p11.2
Domains ig, IGv, IG
Protein Families Secreted Protein, ES Cell Differentiation/IPS, Transmembrane, Adult stem cells, Druggable Genome
Protein Pathways Cell adhesion molecules (CAMs), Antigen processing and presentation, Hematopoietic cell lineage, T cell receptor signaling pathway, Primary immunodeficiency
Gene Summary The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Transcript Variant: This variant (1) encodes the longer, membrane associated isoform (1). Both variants 1 and 3 encode the same isoform (1).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations