CCR6 (NM_004367) Human Untagged Clone

SKU SC109083

CCR6 (untagged)-Human chemokine (C-C motif) receptor 6 (CCR6), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: CCR6
• Synonyms: BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109083 sequence for NM_004367 edited (data generated by NextGen Sequencing); ATGAGCGGGGAATCAATGAATTTCAGCGATGTTTTCGACTCCAGTGAAGATTATTTTGTG; TCAGTCAATACTTCATATTACTCAGTTGATTCTGAGATGTTACTGTGCTCCTTGCAGGAG; GTCAGGCAGTTCTCCAGGCTATTTGTACCGATTGCCTACTCCTTGATCTGTGTCTTTGGC; CTCCTGGGGAATATTCTGGTGGTGATCACCTTTGCTTTTTATAAGAAGGCCAGGTCTATG; ACAGACGTCTATCTCTTGAACATGGCCATTGCAGACATCCTCTTTGTTCTTACTCTCCCA; TTCTGGGCAGTGAGTCATGCCACCGGTGCGTGGGTTTTCAGCAATGCCACGTGCAAGTTG; CTAAAAGGCATCTATGCCATCAACTTTAACTGCGGGATGCTGCTCCTGACTTGCATTAGC; ATGGACCGGTACATCGCCATTGTACAGGCGACTAAGTCATTCCGGCTCCGATCCAGAACA; CTACCGCGCAGCAAAATCATCTGCCTTGTTGTGTGGGGGCTGTCAGTCATCATCTCCAGC; TCAACTTTTGTCTTCAACCAAAAATACAACACCCAAGGCAGCGATGTCTGTGAACCCAAG; TACCAGACTGTCTCGGAGCCCATCAGGTGGAAGCTGCTGATGTTGGGGCTTGAGCTACTC; TTTGGTTTCTTTATCCCTTTGATGTTCATGATATTTTGTTACACGTTCATTGTCAAAACC; TTGGTGCAAGCTCAGAATTCTAAAAGGCACAAAGCCATCCGTGTAATCATAGCTGTGGTG; CTTGTGTTTCTGGCTTGTCAGATTCCTCATAACATGGTCCTGCTTGTGACGGCTGCAAAT; TTGGGTAAAATGAACCGATCCTGCCAGAGCGAAAAGCTAATTGGCTATACGAAAACTGTC; ACAGAAGTCCTGGCTTTCCTGCACTGCTGCCTGAACCCTGTGCTCTACGCTTTTATTGGG; CAGAAGTTCAGAAACTACTTTCTGAAGATCTTGAAGGACCTGTGGTGTGTGAGAAGGAAG; TACAAGTCCTCAGGCTTCTCCTGTGCCGGGAGGTACTCAGAAAACATTTCTCGGCAGACC; AGTGAGACCGCAGATAACGACAATGCGTCGTCCTTCACTATGTGA; ; Clone variation with respect to NM_004367.5;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004367 unedited; CGAGGTTTGTAAACGACTTCTGATAGGCGGCCGACGATTCGGCACGAGGAGCAGTGTGGC; CGGAGAGGAGAGCTGGGCTGGGAGCACAGGAAGGTCCCCAGGACTCTGTGGTCATCAGTA; AGAGAGGGCCCACGTGTATATGCTGGTGAACAGAAATGTCAACCTTTTCAAAGTCTGACA; TTTAAGAGAAAAAACTGTGGCTGTTGGTTTGTTTAACAGACAGCTCCTTCTTTATTGAGT; CACCTCTACTTTCCTGCTACCGCTGCCTGTGAGCTGAAGGGGCTGAACCATACACTCCTT; TTTCTACAACCAGCTTGCATTTTTTCTGCCCACAATGAGCGGGGAATCAATGAATTTCAG; CGATGTTTTCGACTCCAGTGAAGATTATTTTGTGTCAGTCAATACTTCATATTACTCAGT; TGATTCTGAGATGTTACTGTGCTCCTTGCAAGAGGTCAGGCAGTTCTCCAGGCTATTTGT; ACCGATTGCCTACTCCTTGATCTGTGTCTTTGGCCTCCTGGGGAATATTCTGGTGGTGAT; CACCTTTGCTTTTTATAAGAAGGCCAGGTCTATGACAGACGTCTATCTCTTGAACATGGC; CATTGCAGACATCCTCTTTGTTCTTACTCTCCCATTCTGGGCAGTGAGTCATGCCACCGG; TGCGTGGGTTTTCATGCATGCCACGTGCAAGTTGCTAAAAGGCATCTATGCCATCAACTT; TAACTGGCGGATGCTGCTCCTGACTTGCATTAGCATGGACCGGTACATCGCCATTGTACA; GGCGACTAAGTCATTCCCGGCTCCGATCCAGNACACTACCGCGCAGCAAAATCATCTGCC; TTAGTGTGTGGGGGCTGTCAGTCATCATCTCCAGCTCAACTTTTGTCTTCAACCATAATA; CCACAACCCAGGCAGCGATGTCTGGGAA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004367 unedited; CCGCGGCCGCATCTANATCGAGTTTTTTTTTTTTTTTTTTACATGTACAAAACACATTTT; TTATTTTGCAAAGCCAAAGCCATGCTTTAAAAATACAGACTTTGAATCTTAAGACATTAT; TTTGCATTTTAAAGAGAGATATAGTTAAAGCTTACAAGAACAATATAAAGTTTCAAATAA; CACCATTGTCAGGTTTAAACATGTCGGTATGTTTACATGACAGTTCTTTCCTTTTTTTTT; TTTTTTTTTTTTTTGAGAGGGAGTCTCGCTTTGTCACCCAGGCTGGAGTGCAATGGCACG; ATCTCGGGTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTTTTTTGCCTCACCCTCC; CAAGTAGCTGGGATTACAGGCCCCCGCCACCACGCCTGGGAAATTTTTGTATTTTTAGTA; AAGAGGGGTTTCCCCCTGTTGGCCAGGCTGGTCTCAAACTCCTGACCCTCAGAGATCCAC; CCCTCCTGACTTCCTAAAAAGCCGGGATACCAGGTGTGCACCTTCCTTGACTACACTTGG; ACAGTCCTGGTTAACGACACGTCGTCGCTTTCTTTCCCGCTTCTCCTTCCTGCGTCCCTT; CCACATCTCTTGCTCCTTCGCTCTGCCCCGCCTCGCCCCGTGCTAACCTGATATAAATAT; ATTTTCTCCCTTCTTCTTCCCTCCCCCCCATTCCGTCCTTTCCCATCCTCCCTCTCTCTC; TCTCTTCCCGTCTTTCCCCCCCCTCCCACCCTTCCCCCCTCCCCCCCGATACGTTATTCT; GCCGCCACTCTCCCCCTCGCTCATGTTTCGTTTCTCCATACCCCCTCATTTCCCCGTTCC; ATTTCCACACCCANCACTCATATCTCATTTTTCGTCGCTTTCCTCCCCGCCCACCCGTAT; TTTTTTTCATAGTATTCCCCCCTCCCGCCCATATCCCATTCTC;
• Restriction Sites: NotI-NotI
• ACCN: NM_004367
• Insert Size: 3410 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004367.3, NP_004358.2
• RefSeq Size: 3177 bp
• RefSeq ORF: 1125 bp
• Locus ID: 1235
• UniProt ID: P51684
• Cytogenetics: 6q27
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Variants 1 and 2 encode the same protein.