CCR6 (NM_004367) Human Untagged Clone

CAT#: SC109083

CCR6 (untagged)-Human chemokine (C-C motif) receptor 6 (CCR6), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCR6
• Synonyms: BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109083 sequence for NM_004367 edited (data generated by NextGen Sequencing)
  ATGAGCGGGGAATCAATGAATTTCAGCGATGTTTTCGACTCCAGTGAAGATTATTTTGTG
  TCAGTCAATACTTCATATTACTCAGTTGATTCTGAGATGTTACTGTGCTCCTTGCAGGAG
  GTCAGGCAGTTCTCCAGGCTATTTGTACCGATTGCCTACTCCTTGATCTGTGTCTTTGGC
  CTCCTGGGGAATATTCTGGTGGTGATCACCTTTGCTTTTTATAAGAAGGCCAGGTCTATG
  ACAGACGTCTATCTCTTGAACATGGCCATTGCAGACATCCTCTTTGTTCTTACTCTCCCA
  TTCTGGGCAGTGAGTCATGCCACCGGTGCGTGGGTTTTCAGCAATGCCACGTGCAAGTTG
  CTAAAAGGCATCTATGCCATCAACTTTAACTGCGGGATGCTGCTCCTGACTTGCATTAGC
  ATGGACCGGTACATCGCCATTGTACAGGCGACTAAGTCATTCCGGCTCCGATCCAGAACA
  CTACCGCGCAGCAAAATCATCTGCCTTGTTGTGTGGGGGCTGTCAGTCATCATCTCCAGC
  TCAACTTTTGTCTTCAACCAAAAATACAACACCCAAGGCAGCGATGTCTGTGAACCCAAG
  TACCAGACTGTCTCGGAGCCCATCAGGTGGAAGCTGCTGATGTTGGGGCTTGAGCTACTC
  TTTGGTTTCTTTATCCCTTTGATGTTCATGATATTTTGTTACACGTTCATTGTCAAAACC
  TTGGTGCAAGCTCAGAATTCTAAAAGGCACAAAGCCATCCGTGTAATCATAGCTGTGGTG
  CTTGTGTTTCTGGCTTGTCAGATTCCTCATAACATGGTCCTGCTTGTGACGGCTGCAAAT
  TTGGGTAAAATGAACCGATCCTGCCAGAGCGAAAAGCTAATTGGCTATACGAAAACTGTC
  ACAGAAGTCCTGGCTTTCCTGCACTGCTGCCTGAACCCTGTGCTCTACGCTTTTATTGGG
  CAGAAGTTCAGAAACTACTTTCTGAAGATCTTGAAGGACCTGTGGTGTGTGAGAAGGAAG
  TACAAGTCCTCAGGCTTCTCCTGTGCCGGGAGGTACTCAGAAAACATTTCTCGGCAGACC
  AGTGAGACCGCAGATAACGACAATGCGTCGTCCTTCACTATGTGA
  
  Clone variation with respect to NM_004367.5
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004367 unedited
  CGAGGTTTGTAAACGACTTCTGATAGGCGGCCGACGATTCGGCACGAGGAGCAGTGTGGC
  CGGAGAGGAGAGCTGGGCTGGGAGCACAGGAAGGTCCCCAGGACTCTGTGGTCATCAGTA
  AGAGAGGGCCCACGTGTATATGCTGGTGAACAGAAATGTCAACCTTTTCAAAGTCTGACA
  TTTAAGAGAAAAAACTGTGGCTGTTGGTTTGTTTAACAGACAGCTCCTTCTTTATTGAGT
  CACCTCTACTTTCCTGCTACCGCTGCCTGTGAGCTGAAGGGGCTGAACCATACACTCCTT
  TTTCTACAACCAGCTTGCATTTTTTCTGCCCACAATGAGCGGGGAATCAATGAATTTCAG
  CGATGTTTTCGACTCCAGTGAAGATTATTTTGTGTCAGTCAATACTTCATATTACTCAGT
  TGATTCTGAGATGTTACTGTGCTCCTTGCAAGAGGTCAGGCAGTTCTCCAGGCTATTTGT
  ACCGATTGCCTACTCCTTGATCTGTGTCTTTGGCCTCCTGGGGAATATTCTGGTGGTGAT
  CACCTTTGCTTTTTATAAGAAGGCCAGGTCTATGACAGACGTCTATCTCTTGAACATGGC
  CATTGCAGACATCCTCTTTGTTCTTACTCTCCCATTCTGGGCAGTGAGTCATGCCACCGG
  TGCGTGGGTTTTCATGCATGCCACGTGCAAGTTGCTAAAAGGCATCTATGCCATCAACTT
  TAACTGGCGGATGCTGCTCCTGACTTGCATTAGCATGGACCGGTACATCGCCATTGTACA
  GGCGACTAAGTCATTCCCGGCTCCGATCCAGNACACTACCGCGCAGCAAAATCATCTGCC
  TTAGTGTGTGGGGGCTGTCAGTCATCATCTCCAGCTCAACTTTTGTCTTCAACCATAATA
  CCACAACCCAGGCAGCGATGTCTGGGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004367 unedited
  CCGCGGCCGCATCTANATCGAGTTTTTTTTTTTTTTTTTTACATGTACAAAACACATTTT
  TTATTTTGCAAAGCCAAAGCCATGCTTTAAAAATACAGACTTTGAATCTTAAGACATTAT
  TTTGCATTTTAAAGAGAGATATAGTTAAAGCTTACAAGAACAATATAAAGTTTCAAATAA
  CACCATTGTCAGGTTTAAACATGTCGGTATGTTTACATGACAGTTCTTTCCTTTTTTTTT
  TTTTTTTTTTTTTTGAGAGGGAGTCTCGCTTTGTCACCCAGGCTGGAGTGCAATGGCACG
  ATCTCGGGTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTTTTTTGCCTCACCCTCC
  CAAGTAGCTGGGATTACAGGCCCCCGCCACCACGCCTGGGAAATTTTTGTATTTTTAGTA
  AAGAGGGGTTTCCCCCTGTTGGCCAGGCTGGTCTCAAACTCCTGACCCTCAGAGATCCAC
  CCCTCCTGACTTCCTAAAAAGCCGGGATACCAGGTGTGCACCTTCCTTGACTACACTTGG
  ACAGTCCTGGTTAACGACACGTCGTCGCTTTCTTTCCCGCTTCTCCTTCCTGCGTCCCTT
  CCACATCTCTTGCTCCTTCGCTCTGCCCCGCCTCGCCCCGTGCTAACCTGATATAAATAT
  ATTTTCTCCCTTCTTCTTCCCTCCCCCCCATTCCGTCCTTTCCCATCCTCCCTCTCTCTC
  TCTCTTCCCGTCTTTCCCCCCCCTCCCACCCTTCCCCCCTCCCCCCCGATACGTTATTCT
  GCCGCCACTCTCCCCCTCGCTCATGTTTCGTTTCTCCATACCCCCTCATTTCCCCGTTCC
  ATTTCCACACCCANCACTCATATCTCATTTTTCGTCGCTTTCCTCCCCGCCCACCCGTAT
  TTTTTTTCATAGTATTCCCCCCTCCCGCCCATATCCCATTCTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004367
• Insert Size: 3410 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004367.3, NP_004358.2
• RefSeq Size: 3177 bp
• RefSeq ORF: 1125 bp
• Locus ID: 1235
• UniProt ID: P51684
• Cytogenetics: 6q27
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Variants 1 and 2 encode the same protein.