LY108 (SLAMF6) (NM_052931) Human Untagged Clone

SKU SC108856

SLAMF6 (untagged)-Human SLAM family member 6 (SLAMF6), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: LY108
• Synonyms: CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108856 sequence for NM_052931 edited (data generated by NextGen Sequencing); ATGTTGTGGCTGTTCCAATCGCTCCTGTTTGTCTTCTGCTTTGGCCCAGGGAATGTAGTT; TCACAAAGCAGCTTAACCCCATTGATGGTGAACGGGATTCTGGGGGAGTCAGTAACTCTT; CCCCTGGAGTTTCCTGCAGGAGAGAAGGTCAACTTCATCACTTGGCTTTTCAATGAAACA; TCTCTTGCCTTCATAGTACCCCATGAAACCAAAAGTCCAGAAATCCACGTGACTAATCCG; AAACAGGGAAAGCGACTGAACTTCACCCAGTCCTACTCCCTGCAACTCAGCAACCTGAAG; ATGGAAGACACAGGCTCTTACAGAGCCCAGATATCCACAAAGACCTCTGCAAAGCTGTCC; AGTTACACTCTGAGGATATTAAGACAACTGAGGAACATACAAGTTACCAATCACAGTCAG; CTATTTCAGAATATGACCTGTGAGCTCCATCTGACTTGCTCTGTGGAGGATGCAGATGAC; AATGTCTCATTCAGATGGGAGGCCTTGGGAAACACACTTTCAAGTCAGCCAAACCTCACT; GTCTCCTGGGACCCCAGGATTTCCAGTGAACAGGACTACACCTGCATAGCAGAGAATGCT; GTCAGTAATTTATCCTTCTCTGTCTCTGCCCAGAAGCTTTGCGAAGATGTTAAAATTCAA; TATACAGATACCAAAATGATTCTGTTTATGGTTTCTGGGATATGCATAGTCTTCGGTTTC; ATCATACTGCTGTTACTTGTTTTGAGGAAAAGAAGAGATTCCCTATCTTTGTCTACTCAG; CGAACACAGGGCCCCGAGTCCGCAAGGAACCTAGAGTATGTTTCAGTGTCTCCAACGAAC; AACACTGTGTATGCTTCAGTCACTCATTCAAACAGGGAAACAGAAATCTGGACACCTAGA; GAAAATGATACTATCACAATTTACTCCACAATTAATCATTCCAAAGAGAGTAAACCCACT; TTTTCCAGGGCAACTGCCCTTGACAATGTCGTGTAA; ; Clone variation with respect to NM_052931.4;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_052931 unedited; ATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGATTGACTGCCTC; AAGGTCTCAAGCACCAGTCTTCACCGCGGAAAGCTGTTGTGGCTGTTCCAATCGCTCCTG; TTTGTCTTCTGCTTTGGCCCAGGGAATGTAGTTTCACAAAGCAGCTTAACCCCATTGATG; GTGAACGGGATTCTGGGGGAGTCAGTAACTCTTCCCCTGGAGTTTCCTGCAGGAGAGAAG; GTCAACTTCATCACTTGGCTTTTCAATGAAACATCTCTTGCCTTCATAGTACCCCATGAA; ACCAAAAGTCCAGAAATCCACGTGACTAATCCGAAACAGGGAAAGCGACTGAACTTCACC; CAGTCCTACTCCCTGCAACTCAGCAACCTGAAGATGGAAGACACAGGCTCTTACAGAGCC; CAGATATCCACAAAGACCTCTGCAAAGCTGTCCAGTTACACTCTGAGGATATTAAGACAA; CTGAGGAACATACAAGTTACCAATCACAGTCAGCTATTTCAGAATATGACCTGTGAGCTC; CATCTGACTTGCTCTGTGGAGGATGCAGATGACAATGTCTCATTCAGATGGGAGGCCTTG; GGAAACACACTTTCAAGTCAGCCAAACCTCACTGTCTCCTGNNGACCCCAGATTTCCAGT; GAACAGGACTACACCTGCATAGCAGAGAATGCTGNCAGTAATTTATCCTTCTCTGTCTCT; GCCCAAAAGCTTTGCGAAAATGTTNAAATTCATATACAGATACCANNATGATNCTGTTTA; TGGTTTCTGGGATATGCATAGTCTTCGGTTTCATCATACTGCTGTTACCTTGTNNTGAGA; AAGAAGAGATTCCTATCTTTGTCTACTCAGCGACACAG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_052931 unedited; ATGAGCCTGGGGNAGGGGTCACAGGGNATGCCACCCGGGATCTGTTCAGGAAACAGCTAT; GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATTTTATTTATTTATT; TTTTGAGACAGAGTCTCACTCTGTCACCCAGACTGGAATACATTGGCATGATTTTGGCTC; ACTGGAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGTCTCTCAAGTAGCTG; GGATTTTAGGGGTGCACCACCACGCCTGGCTAATTTTTTTGTATTTTTAGTAAAGACGGG; GTTTCACCAAGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTCCCCCCTTG; GCCTCCCAAAGTACTGGGATTACAGGTGTGAGCCACCATGCCCAGCCTAGAAGATTCATT; TTANAAAGAGTGGTCCGGGAAGGTTTCTCTTAAGAGGTGACATATTTAAAATTAACCCTA; ACCAATAGGAGGACCCCATCCCGCCCCAGAAGGGCCTGCCGGAAGATGTAAATTATTTAC; CTCACCAACTTTTTCTTTTAATACAAGCACCCTGAAGAATATCATGGAGGCCTCCTTACA; AAAGTGTCTTAAACGCTCATGGTATCCTTAGGCCTGTAAGTGTGCCCCCACCACCCCCCG; TCCCTGTAAACCGGGTTTCCTTTTTTCACTGGATTGTGTAATCCCCCCCGGGCCTTTTAC; CCCGGTAATCTTGTAGGCACCCCTTTTTTCTCACATTACTATACTCCCGGCATTTCTTAA; GACTAATCTCCTCGTACGAACCCCCCCCACTTACATCGAAGTCAGANCGCTCGTGTTTTT; ACGGGTGTGATTGTTTGTGT;
• Restriction Sites: NotI-NotI
• ACCN: NM_052931
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_052931.3, NP_443163.1
• RefSeq Size: 2776 bp
• RefSeq ORF: 996 bp
• Locus ID: 114836
• UniProt ID: Q96DU3
• Cytogenetics: 1q23.2-q23.3
• Domains: ig, IG
• Protein Families: Druggable Genome, Transmembrane
• Summary: The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]; Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, which results in an isoform (2) that is one amino acid shorter than isoform 1.