TIPRL (NM_152902) Human Untagged Clone

SKU SC100639

TIPRL (untagged)-Human TIP41, TOR signaling pathway regulator-like (S. cerevisiae) (TIPRL), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: TIPRL
• Synonyms: TIP; TIP41; TIPRL1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100639 sequence for NM_152902 edited (data generated by NextGen Sequencing); ATGATGATCCACGGCTTCCAGAGCAGCCACCGGGATTTCTGCTTCGGGCCCTGGAAGCTG; ACGGCGTCCAAGACCCACATCATGAAGTCGGCGGATGTGGAGAAATTAGCCGATGAATTA; CATATGCCATCTCTCCCTGAAATGATGTTTGGAGACAACGTTTTAAGAATCCAGCATGGG; TCTGGCTTTGGAATTGAGTTCAATGCTACAGATGCGTTAAGATGTGTAAACAACTACCAA; GGAATGCTTAAAGTGGCCTGTGCTGAAGAGTGGCAAGAAAGCAGGACGGAGGGTGAACAC; TCCAAAGAGGTTATTAAACCATATGATTGGACCTATACAACAGATTATAAGGGAACCTTA; CTTGGAGAATCTCTTAAGTTAAAGGTTGTACCTACAACAGATCATATAGATACAGAAAAA; TTGAAAGCCAGAGAACAGATTAAGTTTTTTGAAGAAGTTCTCCTTTTTGAGGATGAACTT; CATGATCATGGAGTTTCAAGCCTGAGTGTGAAGATTAGAGTAATGCCTTCTAGCTTTTTC; CTGCTGTTGCGGTTTTTCTTGAGAATTGATGGGGTGCTTATCAGAATGAATGACACGAGA; CTTTACCATGAGGCTGACAAGACCTACATGTTACGAGAATATACGTCACGAGAAAGCAAA; ATTTCTAGTTTGATGCATGTTCCACCTTCCCTCTTCACGGAACCTAATGAAATATCCCAG; TATTTACCAATAAAGGAAGCAGTTTGTGAGAAGCTAATATTTCCAGAAAGAATTGATCCT; AACCCAGCAGACTCACAAAAAAGTACACAAGTGGAATAA; ; Clone variation with respect to NM_152902.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152902 unedited; TTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGAGGGAGGCGG; AGGAACCGGTGTTCGCCGCCGCCGCTGCTTCAGCTTATTCCTTGTGGCCTCTGCGGGTCC; TGCCTCAGCCATGATGATCCACGGCTTCCAGAGCAGCCACCGGGATTTCTGCTTCGGGCC; CTGGAAGCTGACGGCGTCCAAGACCCACATCATGAAGTCGGCGGATGTGGAGAAATTAGC; CGATGAATTACATATGCCATCTCTCCCTGAAATGATGTTTGGAGACAACGTTTTAAGAAT; CCAGCATGGGTCTGGCTTTGGAATTGAGTTCAATGCTACAGATGCGTTAAGATGTGTAAA; CAACTACCAAGGAATGCTTAAAGTGGCCTGTGCTGAAGAGTGGCAAGAAAGCAGGACGGA; GGGTGAACACTCCAAAGAGGTTATTAAACCATATGATTGGACCTATACAACAGATTATAA; GGGAACCTTACTTGGAGAATCTCTTAAGTTAAAGGTTGTACCTACAACAGATCATATAGA; TACAGAAAAATTGAAAGCCAGAGAACAGATTAAGTTTTTTGAAGAAGTTCTCCTTTTTGA; GGATGAACTTCATGATCATGGAGTTTCAAGCCTGAGTGTGAAGATTAGAGTAATGCCTTC; TAGCTTTTTCCTGCTGTTGCGGTTTTTCTTGAGAATTGATGGNGTGCTTATCAGAATGAA; TGACACGAGACTNTACCATGAGGCTGANCAGACCTACATGTTACGAGAATATACGTCACG; AGAAAGCAAAATTTCTAGTTTGATGCATGTTNCCACCTTCCCCTCTCACGGAACCCTATG; AAATATCCCAGTATTTACCATAAAGGAAGCAGTTNGTGAGAAGCTAA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152902 unedited; ACTATGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTATCAGTAAT; TCCTTATTGTTTATTCTCCTCTTACAAAAAGAACTTGGGACAAATAAATACAAAATGGCA; TATATCATATTTAGCAATGGGCAAATACACATTTTCTTGGTATTCTCCACAAGAATAAAC; TAATAAAATTTTCAGAGGCATACTCTTCTACCCATCTCTTACCCTCTAAAAAAAAAAAAG; GCAATTATTTTAATTCCCTGTAATTTTTAACAATGAATTCTCAAAATAAGTAATCTAGGA; CTATTCAGGGACCAAGACATCTGAATCAACAAGTTAAAAAAAAAATGTCTGTATACACAC; ACACACACACACACACACACACACACACACACACACGATGTTGCCCAGAAGCTCCAATTA; ATGAAGAGTCTTAAAAGTTTTTCATTTCATATAGTTTGCATGAATAGAGCCTGTTCTATT; CTAATCTCAATGGCAAATAATATAAAACAGAAAGCTGAACACAACATGTGTGTGTGTGTG; TGTGTGTGTGTGTCTACTTTTCTGTCCTAAGAGAAAACATTAAATACAGGTATATTTAAT; ATACAGTGAACATACCATGTGTTTTCTTAAAGCCAACAAAATCCTGATTTCCTATAGCTT; GGAGGTGATACAGAAGGCAGAAGACAAATATCAAATTTAGCTAATAAAATATACCCTGCC; TATTGGCTCCAGCAATACACTATAGAGTTTGAGCAATGACGGATACCCAAGTGTATATGT; TTTGTTAAAATTTATCTTCAAGCTAATACCTGAAGAGGTTGGCTAATCTTTAAATCAAAT; ATTCTTACTTAAGATTTATCCATCAAATGGAATATGTACAACATATTTCAAATCAGAAAA; GGGTGAATTTTCCCCTGCCCTTTCAAAAAAATTTTAAAATCCCCTGAANAAATTCTTAAT; TG;
• Restriction Sites: NotI-NotI
• ACCN: NM_152902
• Insert Size: 2880 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_152902.3, NP_690866.1
• RefSeq Size: 3032 bp
• RefSeq ORF: 819 bp
• Locus ID: 261726
• UniProt ID: O75663
• Cytogenetics: 1q24.2
• Domains: TIP41
• Summary: TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.