MPP2 (NM_001278374) Human Tagged ORF Clone

SKU RG238077

MPP2 (tGFP-tagged) - Human membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (MPP2), transcript variant 6

Product Data

• Type: Human Tagged ORF Clone
• Target Symbol: MPP2
• Synonyms: DLG2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238077 representing NM_001278374.; Blue=ORF Red=Cloning site Green=Tag(s); ; GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG; GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC; ATGGTGGGCATCCGCAAGACAGCCGGAGAACATCTGGGTGTAACGTTCCGCGTGGAGGGCGGCGAGCTG; GTGATCGCGCGCATTCTGCATGGGGGCATGGTGGCTCAACAAGGCCTGCTGCATGTGGGTGACATCATC; AAGGAGGTGAACGGGCAGCCAGTGGGCAGTGACCCCCGCGCACTGCAGGAGCTCCTGCGCAATGCCAGT; GGCAGTGTCATCCTCAAGATCCTGCCCAGCTACCAGGAGCCCCATCTGCCCCGCCAGGTATTTGTGAAA; TGTCACTTTGACTATGACCCGGCCCGAGACAGCCTCATCCCCTGCAAGGAAGCAGGCCTGCGCTTCAAC; GCCGGGGACTTGCTCCAGATCGTAAACCAGGATGATGCCAACTGGTGGCAGGCATGCCATGTCGAAGGG; GGCAGTGCTGGGCTCATTCCCAGCCAGCTGCTGGAGGAGAAGCGGAAAGCATTTGTCAAGAGGGACCTG; GAGCTGACACCAAACTCAGGGACCCTATGCGGCAGCCTTTCAGGAAAGAAAAAGAAGCGAATGATGTAT; TTGACCACCAAGAATGCAGAGTTTGACCGTCATGAGCTGCTCATTTATGAGGAGGTGGCCCGCATGCCC; CCGTTCCGCCGGAAAACCCTGGTACTGATTGGGGCTCAGGGCGTGGGACGGCGCAGCCTGAAGAACAAG; CTCATCATGTGGGATCCAGATCGCTATGGCACCACGGTGCCCTACACCTCCCGGCGGCCGAAAGACTCA; GAGCGGGAAGGTCAGGGTTACAGCTTTGTGTCCCGTGGGGAGATGGAGGCTGACGTCCGTGCTGGGCGC; TACCTGGAGCATGGCGAATACGAGGGCAACCTGTATGGCACACGTATTGACTCCATCCGGGGCGTGGTC; GCTGCTGGGAAGGTGTGCGTGCTGGATGTCAACCCCCAGGCGGTGAAGGTGCTACGAACGGCCGAGTTT; GTCCCTTACGTGGTGTTCATCGAGGCCCCAGACTTCGAGACCCTGCGGGCCATGAACAGGGCTGCGCTG; GAGAGTGGAATATCCACCAAGCAGCTCACGGAGGCGGACCTGAGACGGACAGTGGAGGAGAGCAGCCGC; ATCCAGCGGGGCTACGGGCACTACTTTGACCTCTGCCTGGTCAATAGCAACCTGGAGAGGACCTTCCGC; GAGCTCCAGACAGCCATGGAGAAGCTACGGACAGAGCCCCAGTGGGTGCCTGTCAGCTGGGTGTAC; ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC;
  Protein Sequence

  >Peptide sequence encoded by RG238077; Blue=ORF Red=Cloning site Green=Tag(s); ; MVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRNAS; GSVILKILPSYQEPHLPRQVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEG; GSAGLIPSQLLEEKRKAFVKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMP; PFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGR; YLEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAAL; ESGISTKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY; TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV; MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED; SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA; FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV;
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001278374
• ORF Size: 1257 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001278374.2
• RefSeq Size: 4526 bp
• RefSeq ORF: 1242 bp
• Locus ID: 4355
• UniProt ID: Q14168
• Cytogenetics: 17q21.31
• Protein Families: Druggable Genome
• MW: 47 kDa
• Summary: Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008]