NAA40 (NM_001300800) Human Tagged ORF Clone

SKU RG236637

NAA40 (tGFP-tagged) - Human N(alpha)-acetyltransferase 40, NatD catalytic subunit (NAA40), transcript variant 2

Product Data

• Type: Human Tagged ORF Clone
• Target Symbol: NAA40
• Synonyms: hNatD; NAT11; NatD; PATT1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG236637 representing NM_001300800.; Blue=ORF Red=Cloning site Green=Tag(s); ; GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG; GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC; ATGGATGCCGTTTGTGCCAAAGTGGACGCTGCCAACAGGCTTGGAGACCCTCTGGAGGCTTTCCCAGTG; TTCAAGAAATATGATAGAAACGGGTTGAATGTCTCCATTGAATGTAAGCGAGTGTCTGGACTGGAGCCA; GCCACCGTGGATTGGGCCTTCGACCTGACCAAAACGAATATGCAAACCATGTATGAGCAGAGCGAGTGG; GGCTGGAAGGACCGAGAGAAACGGGAGGAAATGACAGATGACCGAGCCTGGTACCTCATCGCGTGGGAA; AACAGCTCCGTCCCTGTTGCCTTTTCTCACTTCCGGTTTGACGTGGAGTGTGGGGATGAAGTCCTGTAC; TGCTATGAAGTGCAGTTGGAAAGCAAGGTGCGGCGGAAAGGCCTGGGGAAGTTCCTCATACAGATCCTG; CAGCTCATGGCCAACAGCACACAGATGAAGAAGGTTATGTTAACAGTATTTAAACACAATCATGGTGCC; TACCAGTTCTTCAGAGAAGCGTTGCAATTTGAAATTGATGACTCTTCCCCCAGCATGTCCGGTTGCTGT; GGGGAGGATTGCTCCTATGAGATCCTGAGCCGGAGGACCAAGTTTGGGGACAGCCATCACTCCCACGCG; GGTGGGCACTGTGGTGGCTGCTGCCAC; ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC;
  Protein Sequence

  >Peptide sequence encoded by RG236637; Blue=ORF Red=Cloning site Green=Tag(s); ; MDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEW; GWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQIL; QLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSHHSHA; GGHCGGCCH; TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV; MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED; SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA; FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV;
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001300800
• ORF Size: 658 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001300800.1, NP_001287729.1
• RefSeq Size: 3752 bp
• RefSeq ORF: 651 bp
• Locus ID: 79829
• UniProt ID: Q86UY6
• Cytogenetics: 11q13.1
• MW: 25.2 kDa
• Summary: N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (PubMed:21935442, PubMed:25619998). In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (PubMed:21935442, PubMed:25619998). Acts as a negative regulator of apoptosis (PubMed:26666750). May play a role in hepatic lipid metabolism (By similarity).[UniProtKB/Swiss-Prot Function]