Glyr1 (NM_028720) Mouse Untagged Clone

SKU MC205610

Glyr1 (untagged) - Mouse glyoxylate reductase 1 homolog (Arabidopsis) (Glyr1), transcript variant 2, (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Glyr1
• Synonyms: 2810419J22Rik; 3930401K13Rik; AW545332; Npac
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC006893; GATGGCGGCTGTGAGTCTGCGGCTCGGCGACTTGGTGTGGGGGAAACTGGGCCGGTATCCTCCCTGGCCA GGAAAGATTGTTAATCCACCCAAGGACTTAAAGAAACCACGTGGAAAGAAATGCTTCTTTGTGAAGTTTT TTGGAACAGAAGATCATGCCTGGATCAAAGTGGAACAGCTAAAGCCTTACCATGCTCACAAGGAGGAGAT GATAAAGATTAACAAGGGTAAACGGTTCCAGCAAGCTGTGGATGCTGTTGAAGAGTTCCTCAGGAGAGCC AAAGGGAAAGACCAGACATCATCCCACACTTCTGCTGATGACAAGAATCGGCGTAATTCCAGTGAGGAGA GAAGTAGGCCAAACTCAGGTGATGAGAAACGCAAGCTTAGCCTGTCTGAAGGGAAGGTGAAGAAGAACAT GGGAGAAGGAAAGAAGAGGGTGACTTCAGGCTCTGCAGACAGAGGCTCCAAATGCCTTAAAAGAGCCCAA GAGCAAAGTCCCCGGAAGCGGGGTCGGCCCCCAAAGGATGAGAAGGACCTCACCATCCCTGAGTCTAGCA CTGTAAAGGGGATGATGGCTGGACCGATGGCTGCATTTAAATGGCAGCCAACAGCGACCGAGCCAGTCAA AGATGCAGATCCTCATTTTCATCATTTTCTGTTGAGCCAAACAGAGAAGCCAGCTGTCTGTTACCAGGCA ATCACAAAGAAGTTGAAAATATGTGAAGAGGAAACTGGTTCCACCTCCATCCAGGCAGCAGACAGCACAG CTGTGAATGGCAGCATTACACCCACAGACAAAAAGATAGGATTTTTGGGCCTTGGCTTAATGGGAAGTGG CATCGTCTCCAACTTGCTAAAAATGGGTCACACAGTGACTGTCTGGAACCGGACTGCAGAGAAAGAGGGG GCCCGCCTAGGAAGAACCCCCGCTGAAGTCGTTTCAACTTGTGACATCACTTTTGCCTGTGTGTCGGATC CAAAGGCAGCCAAGGACCTGGTGCTGGGCCCCAGCGGTGTGCTGCAAGGAATCCGCCCCGGGAAGTGCTA TGTGGACATGTCAACGGTGGATGCGGATACAGTCACCGAGCTGGCCCAGGTGATTGTATCCAGAGGGGGA CGCTTTCTGGAAGCACCAGTCTCAGGGAATCAGCAACTGTCCAATGATGGGATGTTGGTGATCTTAGCAG CCGGAGACAGGGGCTTGTATGAGGACTGCAGCAGCTGCTTCCAGGCAATGGGAAAGACCTCCTTCTTTTT AGGTGAAGTTGGCAATGCAGCCAAGATGATGCTGATTGTGAACATGGTCCAAGGGAGCTTCATGGCCACC ATTGCTGAGGGGCTCACGCTGGCCCAAGTGACAGGCCAATCACAGCAGACACTCTTGGACATCCTTAATC AGGGACAATTGGCCAGCATCTTTCTGGACCAGAAGTGCCAAAATATCCTACAAGGAAACTTTAAACCTGA CTTCTACCTGAAATACATTCAGAAGGATCTCCGCCTGGCCATTGCATTGGGTGATGCAGTCAACCACCCC ACTCCCATGGCAGCTGCAGCCAATGAGGTATACAAAAGAGCCAAGGCACTGGACCAGTCTGACAATGATA TGTCTGCCGTGTACCGAGCCTACATACACTAAGCCTTGCCTGCCCATCTACCCTCCCATCTTCCCTCTGA CCTCCCCTCCCAGTGTGGGGTCAGGGTTCTGGGACTAGCTCTGGACCAGTCACCTGTCTCCATTTCCTTT TATACAGACTTTGAAACTTGCATCAGCACAGTACACAGCAGCACCCTGTCTCCCTGAGGCCCTGGCCAGG GATAAGAGGATCTATCTCTCCTGGTGGCTGTGAAGAAGCTCTTGAGCTGGGCCTTGATTGACCCTGGAGC AGGAGGTTGTGGATTCTCTCTGTTCCTCTGTGTTCTCTGTCTCTGTCACACACACACCCAGGATAGAAGC TACCCAGAAACTGCTGCCTGGCTGTTCTTGCAAGCTTAGCCCCCTTCTGGTCAAGAGACTGGAGGGACTA GAATTGACAGGGAGCACTGGAAGCTTTCTTTCAACTTCCCCAGGACAGAGACTGGCCCCCACTGGGCCCC TGAAAGGAGAGGCCCCTCAGCCATCATGAACCAACAGATTCCCTGAGGAGGCTCTGTGGATCACCAGCTG AGGAGGATTTTCCTGTAGACACTACCATTACACCGCAGCTCCCAGAGTGTCTCTGTGAACTGAAGAGAGA CCAGCATAGCCACATAGACCCCTCTTCAGGGGGAGCAGAGTCTACAGTCTTCTGTCCTGAGCCTGTTCCT CCCAGGAGGTTTCATTTGGATTTGCATTCCAGCCCAAGGGAAGGGGCCGTAAGGGCCTTGGGAGCAGTGA AGTGTATGGGCGGCTCCTTCCTGTTTCCGTTACGCCAGGCTCTTGAGCTGGGCTACCTGTTCAGCCTGCT CTACACAGGTCCCCTGCATGTCCCTCTTCCCCTTTTCCTTCCATGGAGATATTTCTGTCCCATCCTCTTT TGACCCAGCCCCAGCCTGATCAACACCAATAATAAGCATTTCCTAGATGAGCATTTCCTAGGCTGGGCTT TTGATGAGGAACCTTACTTCTGCCAGTGGTTCCAAGTTCTGGGTTTTTTGGGACTTGAAGCATTTCTCCT TGAAGAGGGGACCAGAGAGGCTTAGAATGTCACACGAGAGGAATCACCCGAGGAAGCCTTCCTCCTCATG AGTTTGGATTTTCAAAGCCACGATTTAACTTTTCCATCTGGGATAAGGATCTCAGGACATGGGCACGGGG CAGGGGATGCTTGTGGAGTTCAGTGCAATTGTCCATTCACTGGGATGCTGAACAGTTTCTGTCTGGACAC AGCCTGTCTTGGTCCTGGGGGCTGGGGGTGGGGAAGATGCTGTAAGAAAACCGGTTAGTCAATGTTGTCT TAATATTGTTGACAATTCTGTAAAGTTCCTTTTTATGACTATTTCTGTTTAAGCTATTTCACCTTTCATT TTGAAACCCTTTCCTTTTATGGAGAAAATGTGACACTGTGGAAATGCTTGTAAGAAAGCCCCTACTCCCG CTTTTCCTTGAAATGACAGATCTAGGTGATTACGGTTGTGAATTTTTATTTTCACTTTGTTTTTAATGAA CATTTGTCTTTCAGAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_028720
• Insert Size: 1641 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC006893, AAH06893
• RefSeq Size: 3187 bp
• RefSeq ORF: 1641 bp
• Locus ID: 74022
• UniProt ID: Q922P9
• Cytogenetics: 16 2.49 cM
• Summary: Putative oxidoreductase that is recruited on chromatin and promotes KDM1B demethylase activity. Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6.[UniProtKB/Swiss-Prot Function]