Fam213a (NM_027464) Mouse Untagged Clone

CAT#: MC203242

Fam213a (untagged) - Mouse RIKEN cDNA 5730469M10 gene (5730469M10Rik), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fam213a
• Synonyms: 5730469M10Rik; Adrx; AU040822; Pamm
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC056635
  GGCACCTGCGTCCGCTGGCGCAGCTCAGGGGCCAGTGAGGTCCACGGAGGCGGGGTCCTTGGGGCGCAGG ACCCAAGTTTCTTCTCCATGGGTATGTGGTCCATCGGTGTGGGAGCTGTGGGGGCCGCTGCTGTGGCACT GCTCCTGGCCAACACAGACATGTTTCTGTCCAAGCCCCGAAAAGCAGCACTGGAATATTTGGAAGACATA GACCTGAAAACACTGGAGAAAGAACCAAGGACATTCAAAGCAAAGGAGCTGTGGGAGAAGAACGGGGCTG TGATTATGGCTGTACGCAGGCCAGGCTGCTTTCTCTGCCGAGCGGAAGCAGCAGACCTGATGTCCTTGAA GCCCAAGTTGGATGAGCTAGGTGTCCCTCTCTATGCGGTGGTGAAGGAGCAGGTGAAGAGAGAAGTGGAA GATTTCCAACCTTACTTCAAAGGGGAAATCTTCCTGGATGAAAAGAAAAAATTCTATGGTCCAGAGAGGC GGAAGATGATGTTCATGGGCCTCATCCGATTGGGGGTGTGGTATAACTCCTTTCGAGCCTGGAATGGAGG CTTCTCTGGAAACCTAGAAGGCGAAGGCTTCATCCTTGGAGGAGTTTTTGTGATAGGATCTGGAAAACAG GGCATCCTTCTTGAGCACCGAGAAAAAGAATTTGGAGACAGAGTGAACCCACTCTCTGTTCTGGAGGCTG TAAAGAAAATCAAGCTACAGACTCCAGCGTCCGGGAGAAGCTGATCCTGTACAGCTGCTGGCTGGGAGAG AACGCACGGGGCCTGTGCTGTGTTCATCAGATGAGCTGTGCTTTCCCCAGGGCCCCAAGAGCCAGAAGGC CCTTGCACCATATTTACTAAGAATTGGTGATGCATTTTAACATTGTCTGTTTAGGTCCCAGAGCCTTTAA CATTCCGTTTAGGCCCAGTAGGGCAAATAGGGTCCCAGACAGAACAGAGTTCAATCTAACAAACCAGTGA GAGTTATTTGAGGAAAGATCTAGAAAATTTAATGTTTAAAGTTTACTGCTGAAGCTTCTTTCAAAGGAAT ATGTCCTAAGTGCCGGTATTTGAAGTGAAGTTTATTTTCATGCCTAGTTAAAAAACAAACAAACAAACAA ACAAACCTGAAATCTGAGAAAAGTGCGGCTAAGAAACAGCTCAGTGGTGGAGCATTTACCTAACATGCAC ATGGCCCTAAGTGGGATACCCAGACAGACAGACAGACAGACACACACACACACACACACACACACACACA CACACTCTCTCTCTCTCTCCTAAGAAAAGCTGATGGCTGACTTGATAATTAGAGAATTATCCTTTTGTTT GATGTGTTTTCTGTTAACAACTTGTTACTTAAGGTCAGAGTACCACATAAAGCAATTGCTGTGCTGTGTT CTTGGATAAATTACACAGGTAAATTACAAAGTGAAGGTTCTGTGGTCTTCCCTTATAGACGCAGAGATTT GCTTCCTTGGGAAAAACTGTCACCTGGGAAACTGTCACCTCTAATAAAAATATTCACCAGGAAAAAAAAA AAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_027464
• Insert Size: 657 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC056635, AAH56635
• RefSeq Size: 1546 bp
• RefSeq ORF: 657 bp
• Locus ID: 70564
• UniProt ID: Q9CYH2
• Cytogenetics: 14 B
• Gene Summary: Involved in redox regulation of the cell (By similarity). Acts as an antioxidant (By similarity). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (By similarity). May affect bone resorption and help to maintain bone mass (By similarity). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 6, 7, and 8 all encode the same isoform (c).