Fos (NM_010234) Mouse Untagged Clone

SKU MC203181

Fos (untagged) - Mouse FBJ osteosarcoma oncogene (Fos), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Fos
• Synonyms: c-fos; cFos; D12Rfj1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC029814; CAGCGAGCAACTGAGAAGACTGGATAGAGCCGGCGGTTCCGCGAACGAGCAGTGACCGCGCTCCCACCCA GCTCTGCTCTGCAGCTCCCACCAGTGTCTACCCCTGGACCCCTTGCCGGGCTTTCCCCAAACTTCGACCA TGATGTTCTCGGGTTTCAACGCCGACTACGAGGCGTCATCCTCCCGCTGCAGTAGCGCCTCCCCGGCCGG GGACAGCCTTTCCTACTACCATTCCCCAGCCGACTCCTTCTCCAGCATGGGCTCTCCTGTCAACACACAG GACTTTTGCGCAGATCTGTCCGTCTCTAGTGCCAACTTTATCCCCACGGTGACAGCCATCTCCACCAGCC CAGACCTGCAGTGGCTGGTGCAGCCCACTCTGGTCTCCTCCGTGGCCCCATCGCAGACCAGAGCGCCCCA TCCTTACGGACTCCCCACCCAGTCTGCTGGGGCTTACGCCAGAGCGGGAATGGTGAAGACCGTGTCAGGA GGCAGAGCGCAGAGCATCGGCAGAAGGGGCAAAGTAGAGCAGCTATCTCCTGAAGAGGAAGAGAAACGGA GAATCCGAAGGGAACGGAATAAGATGGCTGCAGCCAAGTGCCGGAATCGGAGGAGGGAGCTGACAGATAC ACTCCAAGCGGAGACAGATCAACTTGAAGATGAGAAGTCTGCGTTGCAGACTGAGATTGCCAATCTGCTG AAAGAGAAGGAAAAACTGGAGTTTATTTTGGCAGCCCACCGACCTGCCTGCAAGATCCCCGATGACCTTG GCTTCCCAGAGGAGATGTCTGTGGCCTCCCTGGATTTGACTGGAGGTCTGCCTGAGGCTTCCACCCCAGA GTCTGAGGAGGCCTTCACCCTGCCCCTTCTCAACGACCCTGAGCCCAAGCCATCCTTGGAGCCAGTCAAG AGCATCAGCAACGTGGAGCTGAAGGCAGAACCCTTTGATGACTTCTTGTTTCCGGCATCATCTAGGCCCA GTGGCTCAGAGACCTCCCGCTCTGTGCCAGATGTGGACCTGTCCGGTTCCTTCTATGCAGCAGACTGGGA GCCTCTGCACAGCAATTCCTTGGGGATGGGGCCCATGGTCACAGAGCTGGAGCCCCTGTGTACTCCCGTG GTCACCTGTACTCCGGGCTGCACTACTTACACGTCTTCCTTTGTCTTCACCTACCCTGAAGCTGACTCCT TCCCAAGCTGTGCCGCTGCCCACCGAAAGGGCAGCAGCAGCAACGAGCCCTCCTCCGACTCCCTGAGCTC ACCCACGCTGCTGGCCCTGTGAGCAGTCAGAGAAGGCAAGGCAGCCGGCATCCAGACGTGCCACTGCCCG AGCTGGTGCATTACAGAGAGGAGAAACACGTCTTCCCTCGAAGGTTCCCGTCGACCTAGGGAGGACCTTA CCTGTTCGTGAAACACACCAGGCTGTGGGCCTCAAGGACTTGCAAGCATCCACATCTGGCCTCCAGTCCT CACCTCTTCCAGAGATGTAGCAAAAACAAAACAAAACAAAACAAAAAACCGCATGGAGTGTGTTGTTCCT AGTGACACCTGAGAGCTGGTAGTTAGTAGAGCATGTGAGTCAAGGCCTGGTCTGTGTCTCTTTTCTCTTT CTCCTTAGTTTTCTCATAGCACTAACTAATCTGTTGGGTTCATTATTGGAATTAACCTGGTGCTGGATTG TATCTAGTGCAGCTGATTTTAACAATACCTACTGTGTTCCTGGCAATAGCGTGTTCCAATTAGAAACGAC CAATATTAAACTAAGAAAAGATAGGACTTTATTTTCCAGTAGATAGAAATCAATAGCTATATCCATGTAC TGTAGTCCTTCAGCGTCAATGTTCATTGTCATGTTACTGATCATGCATTGTCGAGGTGGTCTGAATGTTC TGACATTAACAGTTTTCCATGAAAACGTTTTTATTGTGTTTTCAATTTATTTATTAAGATGGATTCTCAG ATATTTATATTTTTATTTTATTTTTTTCTACCCTGAGGTCTTTCGACATGTGGAAAGTGAATTTGAATGA AAAATTTTAAGCATTGTTTGCTTATTGTTCCAAGACATTGTCAATAAAAGCATTTAAGTTGAAAAAAAAA AAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_010234
• Insert Size: 1143 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC029814, AAH29814
• RefSeq Size: 2107 bp
• RefSeq ORF: 1143 bp
• Locus ID: 14281
• UniProt ID: P01101
• Cytogenetics: 12 39.7 cM
• Summary: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling (By similarity). Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.[UniProtKB/Swiss-Prot Function]