Irx5 (NM_018826) Mouse Untagged Clone

SKU MC202002

Irx5 (untagged) - Mouse Iroquois related homeobox 5 (Drosophila) (Irx5), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Irx5
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC051959 sequence for NM_018826; GCAGCCAGAGGCGCGCGGGAAGCCAACCAGGAGGCGCCGCGGGCCGGAGCCCGGGAGCCGGGGCTCGAAG AGCTGCGGCCCGGGGCAGCCAGAAGCCAGGTGCCCTCTCGCTCGCCCTCGCAGGGCGCCGCCCGGCTCGT TGGCCGCCGCGGCGCGGCGCGCCCCATGCCCGTGTGTGGCCATGTCCTACCCGCAGGGCTACTTGTACCA GCCGTCCGCCTCGCTGGCGCTCTACTCGTGCCCCGCATACAGCACCAGCGTCATTTCGGGGCCCCGCACG GATGAGCTCGGCCGCTCTTCTTCGGGCTCCGCGTTCTCGCCCTACGCTGGCTCCACTGCCTTCACGGCTC CCTCGCCCGGCTACAACTCGCACCTCCAGTACGGCGCCGACCCCGCGGCTGCGGCCGCCGCTGCCTTCTC TTACGTGGGCTCTCCCTACGACCACACTCCCGGTATGGCAGGTTCCTTGGGATATCACCCTTATGCAGCA CCTCTGGGCTCCTATCCTTATGGGGACCCCGCGTACCGGAAGAATGCCACTCGGGACGCTACAGCCACTC TCAAGGCCTGGCTCAACGAGCACCGCAAGAACCCGTACCCCACCAAGGGAGAGAAGATCATGCTGGCCAT TATCACCAAGATGACCCTCACCCAGGTGTCCACCTGGTTTGCCAACGCGCGCCGGCGCCTCAAGAAAGAG AACAAGATGACGTGGACGCCACGGAACCGCAGCGAGGACGAGGAGGAGGAGGAGAACATCGATCTGGAGA AGAACGACGAGGACGAGCCACAGAAGCCCGAGGACAAGGGCGACCTCGAGGGCCCCGAATCAGGAGGAGC AGAGCAGAAGGCGACTGCGGGCTGCGAACGGCTGCAGGGGCCGCTCAGCCCCGCCGGCAAGGAGACCGAA GGCAGCCTCAGCGACTCGGATTTTAAGGAGTCGTCCTCCGAAGGCCGCCACGATGAGCTGCCCAGGCCCC CGCGCGCGGGCGAGTCCTCCCCGGCTGGGCCCGCAACCGCTCGTCTGGCGGAAGACGCGGGTCCTCACTA CCCCGCGAGTGTGCCGGCTCCCGGCCCGCACCCATCAGCCGGAGAGCTGCCCCCCGGCTCGGGCGGATCC TCGGTCATCCACTCGCCACCGCCACCTCCGCCACCGCCTCCGGCCGTGCTAGCCAAGCCCAAACTGTGGT CTCTGGCCGAGATCGCCACATCCTCGGACAAGGTCAAGGACGGGGGCGGAGGGAGCGAGGGCTCTCCATG CCCACCGTGCCCAGGGCCCATGGGCGGGCAAACGCTTGGAGGCAGCCGCGCGTCTCCTGCCCCAGCGCCC GCACGCTCACCCTCCGCGCAGTGTCCCTTTCCGGGCGGGACGGTGCTGTCCCGGCCTCTTTATTACACGG CGCCCTTCTATCCGGGCTACACGAACTATGGCTCCTTCGGACATCTTCACGGCCACCCAGGGCCAGGGCC AAGCCCTACAGCGGGTCCTGGCTCTCATTTCAATGGATTAAACCAGACGGTGTTGAATCGTGCGGACGTT TTGGCTAAAGACCCGAAAATGTTGCGGAGCCAGTCTCAGCTAGACCTGTGCAAAGACTCCCCCTATGAGT TGAAGAAAGGTATGTCCGACATTTAACTCTGGTGCGGTATCCCCGGACTTTCCTAATTTATTAAAACCAT GGCCTTGGCAGTTATTTTTCCATCACCAAGAGAGAGAAAGAAAAAAGAAATAAACTACCCCTCTTATTCA GAAGTTTATAGTTTATGGAGATGGATGGCATAAAAATGTATACATCTCCACACTCGAAAAAATTGTTTTA GCCAACTGAAAAGAAAAAAAAACTTAAAAGGATTTGTATTAAATCTTATTCTGTATATTTAATGTAGCAT TTTTGTATTTAAATTGATAATTCAGTATCTTTGAAGTAAATTATGAAATCAAGACACCTGTACAGGCATT TAATGTTTTTGTAATATAAATATATACATTTGTGTTCCCCCAAAACTGTTTCATAGTTTAAAAATACAAG TTTAATTTAATTTTTTACACCTATTGATTTTTTTCCTGGGTATGAGCTAAAATATTATTACAGAAAGGAA GCAGGTTATACGCTTAGATTTAAAAAAAAAAGTAAGAGAAACTGCAGTGGTCTTTGTAAAATGCAAAATA TTTAATTAAAGGAGATTTTAACATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_018826
• Insert Size: 1455 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.; ; The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC051959, AAH51959
• RefSeq Size: 2225 bp
• RefSeq ORF: 1455 bp
• Locus ID: 54352
• UniProt ID: Q9JKQ4
• Cytogenetics: 8 44.93 cM
• Summary: Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina. Involved in craniofacial and gonadal development (By similarity). Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12.[UniProtKB/Swiss-Prot Function]