Cldn6 (NM_018777) Mouse Untagged Clone

SKU MC201867

Cldn6 (untagged) - Mouse claudin 6 (Cldn6), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Cldn6
• Synonyms: AL024037
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC050138 sequence for NM_018777; GGAAATCTTAGCAGTCTCTTTTGCAGGCTCGGATATCAGGGGTGGCCGAACCGGACTGGACGTCCGCAGA CAAAGCTGACCGAGCACTCGCCCCCTCAACCTCATCATGGCCTCTACTGGTCTGCAAATCTTGGGGATCG TCCTGACCCTGCTTGGCTGGGTCAACGCCCTGGTGTCCTGTGCCCTGCCCATGTGGAAGGTGACCGCCTT CATCGGCAACAGCATCGTCGTGGCCCAGATGGTGTGGGAGGGGCTGTGGATGTCCTGTGTGGTTCAGAGC ACTGGCCAGATGCAGTGCAAGGTGTATGACTCACTGTTGGCGCTGCCCCAGGACCTGCAGGCTGCCAGAG CCCTCTGTGTTGTCACCCTCCTCATTGTCCTGCTTGGCCTGCTCGTGTACCTGGCTGGAGCCAAGTGCAC TACCTGTGTGGAAGATAGGAACTCCAAGTCTCGTCTGGTGCTCATCTCTGGCATCATCTTTGTCATTTCT GGGGTCCTGACGCTCATTCCTGTCTGCTGGACTGCCCACTCTATCATCCAGGACTTCTACAACCCCTTGG TGGCTGATGCTCAAAAGCGGGAGCTGGGGGCCTCCCTCTACCTGGGCTGGGCAGCCTCAGGCCTTTTGCT GCTGGGTGGAGGGCTACTATGCTGCGCCTGCTCTTCTGGAGGGACCCAGGGACCCAGACATTACATGGCC TGCTATTCTACATCTGTCCCACATTCTCGGGGACCCCCCGAATATCCCACCAAGAATTATGTGTGATGCT CACTGGGGAGTGAGGCTCTGCTAGCCAGGGAACCTGAGCTGAGCCATCAAGAAAGGTTACGGAGTAGTTT GGGGGTTGTCTTATTTCTTGTTTTTCTTTTGTACTACTGGGTATTGAACCTGGGGCCCCACGCATTTGGT AGGCAAGCACTCACCAGTGAGTCATGTGGTGCCCTGTCTGTCCCTAGGGTTTGTTCCACCTGTTTTTGAG ACAAGCTCTTCTCATGGAGCTCTGATCGACCTCCAGCTCCAGTTTTCCTGCCTCAACCTGAGTCCAAGCT CCACCTCTCTCTCTGCTGCTGGCATTTCTCACTTTTAGCTACTGAGGCTGGGAGGATGGGACACTTGAGT TTCTGCGTCATTATTCATTCTGGGGATCTTCTGTGCAGTGTTCTAAGGCTGCCTGGCCTTTGTTTTTCTC AAAATATCCTGTCCCAGTCCCAAGAGTTCCTGCTGTGGCCGGAGGTAACTCACAGGACAGACGCACCCCT TCCTGGTCAGACTTCTCTCCAGCCCTGGAAGGGCAGGTGATAAGTTACCAAGGAATTTTCTACCCTGAGA CTTCCAACCTTTGGCCCCTGAATCCCATCGCCAAGGTTACTGTGTACTCTCCCTACAAAAGGTCCCAGCT GTGCTGTAGACCCTCCTCCCCCACACCTTGCACACTTCCCTGCTCACACAATGCTTTACTAAATAAAACA TGATTTTTTTTCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_018777
• Insert Size: 660 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC050138, AAH50138
• RefSeq Size: 1512 bp
• RefSeq ORF: 660 bp
• Locus ID: 54419
• UniProt ID: Q9Z262
• Cytogenetics: 17 A3.3
• Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is essential for blastocyst formation in preimplantation mouse embryos, and is invloved in and is crucial for the formation and maintenance of the epidermal permeability barrier. This gene is adjacent to another family member Cldn9 on chromosome 17. [provided by RefSeq, Aug 2010]