Tspan14 (NM_145928) Mouse Untagged Clone

SKU MC201596

Tspan14 (untagged) - Mouse tetraspanin 14 (Tspan14), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Tspan14
• Synonyms: AA958793; D14Ertd226e; Tm4sf14; tspan-14
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC025568 sequence for NM_145928; CCACGCGTCCGCCGGGCCGTGCTGCCGCCGCTGCTGCCGCGCCCGGGTCCTCCTTCTCAGAAGATGCACT ATTATAGATACTCGAACGCCGAGGTCAGCTGCTGGTACAAGTACCTGCTCTTCAGCTACAATATCGTCTT TTGGCTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGCTGTCCGAC CTCACCAAGGTGACCCGGTTGCATGGAATCGACCCCGTCGTGCTGGTCTTGATGGTGGGCGTGGTGATGT TCACACTGGGATTCGCAGGCTGTGTCGGGGCCCTCCGAGAGAACATCTGCCTGCTCAAGTTTTTCTGTGG GGCCATTGTGCTCATCTTCTTCCTGGAACTGGCCGTGGCCGTGTTGGCCTTTTTATTCCAAGACTGGGTG AGAGACCGGTTCCGGGAATTCTTCGAGAGCAACATCAAGTCCTATCGGGATGACATCGACCTGCAGAACC TCATTGACTCCCTTCAGAAAGCTAATCAGTGCTGCGGGGCTTACGGCCCTGAAGACTGGGACCTCAATGT CTACTTCAACTGCAGTGGTGCCAGCTACAGCCGAGAGAAATGTGGGGTACCCTTCTCCTGCTGTGTGCCA GATCCTGCACAAAAAGTCGTGAACACACAGTGTGGCTATGATGTCCGGATTCAGCTGAAGAGCAAGTGGG ATGAGTTCATCTTTACAAAAGGATGCATCCAGGCTCTGGAAGGCTGGCTGCCCAGGAACATCTACATTGT GGCTGGTGTCTTCATTGCCATCTCACTGCTGCAGATTTTTGGCATCTTCCTGGCGAGGACCCTGATCTCA GACATCGAGGCAGTGAAGGCAGGCCATCACTTCTGAGAAGCAGATGCAGCAAATGGAGTTGAGCCACATG TAGAGGTCAAGCCTTTCACTGTCCAGCAGCAGCAGCAGAAGTCGACATTAGCCACCCACAACCAGACCCC AGTCTTCGGCATCAGTGTGATATGACCTCTCAGTTTCTTCTTGCTGGTGCTGAAGACCAAGGCCCCTTCT CATCTGCCCACACTTGACATGGCATCTCTGAAAAGGGCTTGCCCAGAGACAGAGAATGTGTTTTTATGTG GAGTAGTAACTCTGAGGACAGATGGCTCCCATGGCTGCAGGAAAGGCTTGATGGCCCTTATGGAGCCCAA GAGCATCTGCAGGCCTCTGCCTCCTCAGTAAGGCTTAGGTAGATGCTCAGCTCATATCTTCTGTGGGTAT AGCATCAGTATGGGACCAGCACTGAGGACAAGGCTTCTGGTTCCATCTGATCAAGAAGGAGGAGGAGGGA TGAGTGGTCTAGTGGTACCCTCGTGCCAACAGGGTTCGTGGTGGTGCAAACATGCCAGGGGTTTGCAGAA TCCTCAGCCATGTCCAAGTGAATTATGCCTGAGCCAGCCATAGCCGGTCCTGGGGAGCACATCACCACTG CCTTCCAAGCCTACACTGCTCTCCCAGGGTAGAACAGCCTCGTTTCTCCATAGCATTAAGCCCTACTGAG GGCCAGCTCTCCTGTTCTTATAGTGTGTAAATAGTTTATTTATAGGGGTAAGAGTGTTCCTTCACCATAT CTTCATAGCCTCTTCCGTCTGGCATTCTTTTCTCAGCAGCCTTACCCAGTGTCTGGGACCAAGCTGTCCT TTTCAGTTCCCCGAGTGTCTTAAGAACCAGCTGTGACAGCTTCTCCCTCTGGTTCACATCCCCTCCATGC GCCCCTGCTTGGCTTCCCTGTCTTCTGGTCTCGGTGCTACTGAAATGGCCACCAGAACTTGAATCCTGAC TGACCCTTTCTCCTTCCCCGCTGCCCTCCAGGGAGCCCCAGCTCCTGATTGCCAGCTGGAAACTGGGTTC CTCTCACGACCACATACAGCTAGTGGCCCAAAGTATGCTGTCCCTGGAGGGCAACGCTCCTGCAGCCAGG CCCTGGCAAGCACAGACAGCTGGTGCTGTGTGGAATGCTCAGTGCATCTTATCTCTAACTTCCGTGGTGA CTCCCCCACCCACATGCCGTGTTCACTGTCAGCACTGTTCTGAGGCTGCTCTTGAAAATGATGTCTGTCT TACGTACTGGATACTCCGAGGCATGCTGGCGTCTGTCCACCTGGGGCTGGGCTACTCTCTAGTGCTTCTT TATAACTTGTATCTGTCCTTACCGTTCAGGGATTGAGTACTACCTTCAGTTACTTGCCGAAGTGTACATT CTAGTGTGGTGTATACTGGTGATACTGGTGGGGGTGTGTTCATGATGATGATGATGTTATAATTTTCTAA ATAATTCTCTATAGACTAGAGGAAGAAGAATGCTTGTGTTTTTAGGAAGTGTGCAGCTTCTCTTTGACCT GCCAAACTCTTTTATGGAATATATCTTTATATTAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_145928
• Insert Size: 813 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC025568, AAH25568
• RefSeq Size: 2428 bp
• RefSeq ORF: 813 bp
• Locus ID: 52588
• UniProt ID: Q8QZY6
• Cytogenetics: 14 22.36 cM
• Summary: Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26668317, PubMed:23035126). Negatively regulates ADAM10-mediated cleavage of GP6 (PubMed:26668317). Promotes ADAM10-mediated cleavage of CDH5 (PubMed:23035126).[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.