LYPD6B (NM_177964) Human 3' UTR Clone

SKU SC207649

3' UTR clone of LY6/PLAUR domain containing 6B (LYPD6B) for miRNA target validation

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Target Symbol: LYPD6B
• Synonyms: CT116; LYPD7
• ACCN: NM_177964
• Insert Size: 582 bp
• Sequence Data:
  Insert Sequence

  >SC207649 3’UTR clone of NM_177964 ; The sequence shown below is from the reference sequence of NM_177964. The complete sequence of this clone may contain minor differences, such as SNPs.; Blue=Stop Codon Red=Cloning site; ; GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG; TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC; GCCTGGGTCTTTGTGCTTCCATTGCTGTGATGCCACCATTCCTAGGAGAGGCAGAGACCAGCCTCTAAA; GCACAAGCCAAAAACTGTGTGAACGGTGAACTTTGGAGTGAAGATCAATCTTGCACTTGGTGAAGAGTG; CACATTGGACCTCAAGGCGAAAGCCAGTGGTTTGCTTGGATAAAATGTTCCCGCATGAGGCCACAGGAC; TGAGGATGGGAATTTGGCAGGGCCTGAGAAGATGGTCTGACTTCCAGGCTTCCTGGTCAAAGAGAGCTA; CGTTTGGGCAGTTCTGCAGAGAGGATCCTGGCAACTAGTCCCACCTGACTAGGCCTTTAGCTGAAAGGA; TTTCTTGACCTCCTTGACTGCCTCAGAGGCTGCCAGGTCAAACCCTCTTGTTTATGTGATTAGCTCAGA; GCATCTCTATGAAATCTAACCCTTCCCCTCATGAGAAAGCAGTTTTCCCCACCAACAGCATAGTCAATG; AGAAAGGCAACTGTACGAAGAAAACTTCCAGTGGAACTAATATGAAATCTATTTGCAAATTATGGGGGG; AAATAAAGCTTTTAAATTATACAATGTAAA; ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA; CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG;
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_177964.5
• Locus ID: 130576
• Summary: Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.[UniProtKB/Swiss-Prot Function]