VR1 (TRPV1) Rabbit Polyclonal Antibody

SKU TA890016

Rabbit polyclonal anti-TRPV1 Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human TRPV1
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 1.48mg/ml
• Purification: Purified from the immunized serum by affinity chromatography (Protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 94.8 kDa
• Gene Name: transient receptor potential cation channel subfamily V member 1
• Database Link:
  NP_542435
  Q8NER1
• Background: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: VR1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction