gamma Catenin (JUP) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4D5]

SKU TA812398AM

JUP mouse monoclonal antibody,clone OTI4D5, Biotinylated

Product Data

• Clone Name: OTI4D5
• Application: IHC, WB
• Recommended Dilution: WB 1:500, IHC 1:2000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 500-745 of human JUP (NP_002221) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 81.6 kDa
• Gene Name: junction plakoglobin
• Database Link:
  NP_002221
  P14923
• Background: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
• Synonyms: CTNNG; DP3; DPIII; PDGB; PG; PKGB

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer