Optineurin(OPTN) Mouse Monoclonal Antibody [Clone ID: OTI7H2]

CAT#: TA812132

OPTN mouse monoclonal antibody,clone OTI7H2


 Product Datasheet for 'TA812132'

  View other "OTI7H2" antibodies (1)

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USD 360.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI7H2
Applications WB, IHC
Recommend Dilution WB 1:2000, IHC 1:500,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human OPTN (NP_001008212) produced in HEK293T cell.
Isotype IgG1
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 65.7 kDa
Gene Name optineurin
Background This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
Synonyms ALS12|FIP2|GLC1E|HIP7|HYPL|NRP|TFIIIA-INTP
Reference Data
Protein Families Druggable Genome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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