GPNMB Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2A10]

SKU TA807766AM

GPNMB mouse monoclonal antibody, clone OTI2A10 (formerly 2A10), Biotinylated

Product Data

• Clone Name: OTI2A10
• Application: IHC, WB
• Recommended Dilution: WB 1:500, IHC 1:150
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human GPNMB (NP_001005340) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 61.5 kDa
• Gene Name: glycoprotein nmb
• Database Link:
  NP_001005340
  Q14956
• Background: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: HGFIN; NMB

Reference Data

• Protein Families: Druggable Genome, Transmembrane