Macrophage Scavenger Receptor I (MSR1) Mouse Monoclonal Antibody [Clone ID: OTI9E5]

SKU
TA802777
MSR1 mouse monoclonal antibody, clone OTI9E5 (formerly 9E5)
  • TrueMAB

    Antibodies made against full-length proteins as antigens.

    Click here to learn more.

$447.00
In Stock*
Specifications
Product Data
Clone Name OTI9E5
Application WB
Recommended Dilution WB 1:2000
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 197-451 of human MSR1(NP_619730) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 42.8 kDa
Gene Name macrophage scavenger receptor 1
Database Link
Background This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008]
Synonyms CD204; phSR1; phSR2; SCARA1; SR-A; SRA
Reference Data
Protein Families Druggable Genome, Transmembrane
Write Your Own Review
You're reviewing:Macrophage Scavenger Receptor I (MSR1) Mouse Monoclonal Antibody [Clone ID: OTI9E5]
Your Rating
SKU Description Size Price
CF802777 Carrier-free (BSA/glycerol-free) MSR1 mouse monoclonal antibody, clone OTI9E5 (formerly 9E5) 100 ug
$600.00
TA802777AM MSR1 mouse monoclonal antibody,clone 9E5, Biotinylated 100 ul
$509.00
TA802777BM MSR1 mouse monoclonal antibody,clone 9E5, HRP conjugated 100 ul
$509.00
TA802777S MSR1 mouse monoclonal antibody, clone OTI9E5 (formerly 9E5) 30 ul
$200.00

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.