p63 (TP63) Mouse Monoclonal Antibody [Clone ID: OTI4E7]
SKU
TA802078
TP63 mouse monoclonal antibody, clone OTI4E7 (formerly 4E7)
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TrueMAB™
Antibodies made against full-length proteins as antigens.
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Product Data | |
Clone Name | OTI4E7 |
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Application | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human TP63 (NP_003713) produced in SF9 cell. |
Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 76.6 kDa |
Gene Name | tumor protein p63 |
Database Link | |
Background | This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008] |
Synonyms | AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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Product Manuals |
FAQs |
SDS |
Antibody Resources |
SKU | Description | Size | Price | |
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CF802078 | Carrier-free (BSA/glycerol-free) TP63 mouse monoclonal antibody, clone OTI4E7 (formerly 4E7) | 100 ug |
$600.00
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TA802078AM | TP63 mouse monoclonal antibody,clone 4E7, Biotinylated | 100 ul |
$509.00
|
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TA802078BM | TP63 mouse monoclonal antibody,clone 4E7, HRP conjugated | 100 ul |
$509.00
|
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TA802078S | TP63 mouse monoclonal antibody, clone OTI4E7 (formerly 4E7) | 30 ul |
$200.00
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.