EMA (MUC1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4A5]

CAT#: TA800838AM

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MUC1 mouse monoclonal antibody,clone 4A5, Biotinylated



  View other "OTI4A5" antibodies (6)

USD 509.00


Availability*
5 Days

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI4A5
Applications IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MUC1 (NP_001018016) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 25.1 kDa
Gene Name mucin 1, cell surface associated
Background This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
Synonyms ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; SEC
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane

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