E Cadherin (CDH1) Mouse Monoclonal Antibody [Clone ID: OTI4F1]
CDH1 mouse monoclonal antibody,clone OTI4F1
View other "OTI4F1" antibodies (6)
Special Offer: Try sample size of this antibody at $99/€99. Use code “TrueSample”.
Specifications
Product Data | |
Clone Name | OTI4F1 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CDH1 (NP_004351) produced in HEK293T cell. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 94.8 kDa |
Gene Name | cadherin 1 |
Database Link | |
Background | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008] |
Synonyms | Arc-1; CD324; CDHE; ECAD; LCAM; UVO |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Adherens junction, Bladder cancer, Cell adhesion molecules (CAMs), Endometrial cancer, Melanoma, Pathogenic Escherichia coli infection, Pathways in cancer, Thyroid cancer |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF800692 | Carrier-free (BSA/glycerol-free) CDH1 mouse monoclonal antibody,clone OTI4F1 |
USD 545.00 |
|
TA600196 | CDH1 mouse monoclonal capture antibody, validated for ELISA and Luminex assays |
USD 428.00 |
|
TA700196 | CDH1 biotinylated mouse monoclonal detection antibody, validated for Luminex assays |
USD 461.00 |
|
TA800692AM | CDH1 mouse monoclonal antibody,clone 4F1, Biotinylated |
USD 462.00 |
|
TA800692BM | CDH1 mouse monoclonal antibody,clone 4F1, HRP conjugated |
USD 462.00 |
|
TA800692S | CDH1 mouse monoclonal antibody,clone OTI4F1 |
USD 186.00 |