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Von Hippel Lindau (VHL) Mouse Monoclonal Antibody [Clone ID: OTI1E1]

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SKU
TA506222
VHL (Von Hippel Lindau) mouse monoclonal antibody, clone OTI1E1 (formerly 1E1)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

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View other "Von Hippel Lindau or NM_000551" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1E1
Application IHC, WB
Recommended Dilution WB 1:4000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human VHL(NP_000542) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 24 kDa
Gene Name von Hippel-Lindau tumor suppressor
Database Link
Background Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. provided by RefSeq, Jul 2008
Synonyms HRCA1; pVHL; RCA1; VHL1
Reference Data
Protein Categories Cancer: Bladder, Cancer: Endocrine, Cardiovascular diseases, Cytokines, Intracellular Proteins
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Renal cell carcinoma, Ubiquitin mediated proteolysis
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Other "OTI1E1" antibodies (4)
SKU Description Size Price
CF506222 Carrier-free (BSA/glycerol-free) VHL mouse monoclonal antibody, clone OTI1E1 (formerly 1E1) 100 ug
$620.00
TA506222AM VHL mouse monoclonal antibody,clone 1E1, Biotinylated 100 ul
$509.00
TA506222BM VHL mouse monoclonal antibody,clone 1E1, HRP conjugated 100 ul
$509.00
TA506222S VHL (Von Hippel Lindau) mouse monoclonal antibody, clone OTI1E1 (formerly 1E1) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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