Granzyme B (GZMB) Mouse Monoclonal Antibody [Clone ID: OTI4E6]
Specifications
| Product Data | |
| Clone Name | OTI4E6 |
|---|---|
| Application | ELISA (indirect), IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21-247 of human GZMB(NP_004122) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | granzyme B |
| Database Link | |
| Background | Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. provided by RefSeq, Jul 2008 |
| Synonyms | C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT |
| Reference Data | |
| Protein Categories | ADC Targets, Cytokines, Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4E6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF505930 | Carrier-free (BSA/glycerol-free) GZMB mouse monoclonal antibody,clone OTI4E6 | 100 ug |
$620.00
|
|
| TA505930 | GZMB mouse monoclonal antibody,clone OTI4E6 | 100 ul |
$447.00
|
|
| TA505930AM | GZMB mouse monoclonal antibody,clone 4E6, Biotinylated | 100 ul |
$509.00
|
|
| TA505930BM | GZMB mouse monoclonal antibody,clone 4E6, HRP conjugated | 100 ul |
$509.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.