HLCS Mouse Monoclonal Antibody [Clone ID: OTI1E4]

SKU TA504422

HLCS mouse monoclonal antibody, clone OTI1E4 (formerly 1E4)

Product Data

• Clone Name: OTI1E4
• Application: FC, IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:150, FLOW 1:100
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human HLCS(NP_000402) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 80.6 kDa
• Gene Name: holocarboxylase synthetase
• Database Link:
  NP_000402
  P50747
• Background: This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Synonyms: HCS

Reference Data

• Protein Pathways: Biotin metabolism, Metabolic pathways