BCAT1 Mouse Monoclonal Antibody [Clone ID: OTI3F5]

SKU TA504360S

BCAT1 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5)

Product Data

• Clone Name: OTI3F5
• Application: IHC, WB
• Recommended Dilution: WB 1:500~2000, IHC 1:150
• Reactivity: Dog, Human, Mouse
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human BCAT1(NP_005495) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.78 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 42.8 kDa
• Gene Name: branched chain amino acid transaminase 1
• Database Link:
  NP_005495
  P54687
• Background: This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq]
• Synonyms: BCATC; BCT1; ECA39; MECA39; PNAS121; PP18

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: leucine and isoleucine biosynthesis, leucine and isoleucine degradation, Metabolic pathways, Pantothenate and CoA biosynthesis, Valine