Estrogen Receptor 1(ESR1) Mouse Monoclonal Antibody [Clone ID: OTI1B1]

CAT#: TA503759

ESR1 (Estrogen Receptor 1/ER) mouse monoclonal antibody, clone OTI1B1 (formerly 1B1)

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 Product Datasheet for 'TA503759'

USD 379.00


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI1B1
Applications WB, IHC
Recommend Dilution WB 1:2000, IHC 1:150,
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ESR1(NP_000116) produced in HEK293T cell.
Isotype IgG2b
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 66 kDa
Gene Name estrogen receptor 1
Background This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008].
Synonyms ER|ESR|ESRA|ESTRR|Era|NR3A1
Reference Data
Protein Families Nuclear Hormone Receptor, Transcription Factors, Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations