PKC epsilon (PRKCE) Mouse Monoclonal Antibody [Clone ID: OTI2A12]
SKU
TA502437
PRKCE (PKC epsilon ) mouse monoclonal antibody, clone OTI2A12 (formerly 2A12)
-
TrueMAB™
Antibodies made against full-length proteins as antigens.
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Product Data | |
Clone Name | OTI2A12 |
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Application | FC, IF, IHC, WB |
Recommended Dilution | WB 1:1000~2000, IHC 1:150, IF 1:100, FLOW 1:100 |
Reactivity | Dog, Human, Monkey, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PRKCE (NP_005391) produced in HEK293T cell. |
Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.83 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 83.5 kDa |
Gene Name | protein kinase C epsilon |
Database Link | |
Background | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq] |
Synonyms | nPKC-epsilon; PKCE |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction |
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FAQs |
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Antibody Resources |
SKU | Description | Size | Price | |
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CF502437 | Carrier-free (BSA/glycerol-free) PRKCE mouse monoclonal antibody, clone OTI2A12 (formerly 2A12) | 100 ug |
$600.00
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TA502437AM | PRKCE (PKC epsilon ) mouse monoclonal antibody, clone OTI2A12 (formerly 2A12), Biotinylated | 100 ul |
$509.00
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TA502437BM | PRKCE (PKC epsilon ) mouse monoclonal antibody, clone OTI2A12 (formerly 2A12), HRP conjugated | 100 ul |
$509.00
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TA502437S | PRKCE (PKC epsilon ) mouse monoclonal antibody, clone OTI2A12 (formerly 2A12) | 30 ul |
$200.00
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TA700072 | PRKCE biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays | 50 ug |
$494.00
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.