QPRT Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C10]

SKU TA501524BM

QPRT mouse monoclonal antibody, clone OTI1C10 (formerly 1C10), HRP conjugated

Product Data

• Clone Name: OTI1C10
• Application: FC, IF, IHC, WB
• Recommended Dilution: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 30.6 kDa
• Gene Name: quinolinate phosphoribosyltransferase
• Database Link:
  NP_055113
  Q15274
• Background: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
• Synonyms: HEL-S-90n; QPRTase

Reference Data

• Protein Pathways: Metabolic pathways, Nicotinate and nicotinamide metabolism