QPRT Mouse Monoclonal Antibody [Clone ID: OTI1C10]

SKU CF501524

Carrier-free (BSA/glycerol-free) QPRT mouse monoclonal antibody, clone OTI1C10 (formerly 1C10)

Product Data

• Clone Name: OTI1C10
• Application: FC, IF, IHC, WB
• Recommended Dilution: WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 30.6 kDa
• Gene Name: quinolinate phosphoribosyltransferase
• Database Link:
  NP_055113
  Q15274
• Background: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
• Synonyms: HEL-S-90n; QPRTase

Reference Data

• Protein Pathways: Metabolic pathways, Nicotinate and nicotinamide metabolism