GNMT Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI8A3]

SKU TA501276AM

Anti-GNMT mouse monoclonal antibody, clone OTI8A3 (formerly 8A3), Biotinylated

Product Data

• Clone Name: OTI8A3
• Application: FC, WB
• Recommended Dilution: WB: 1:200 - 1:1000, Flow 1:100
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG3
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human GNMT (NP_061833) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 32.6 kDa
• Gene Name: glycine N-methyltransferase
• Database Link:
  NP_061833
  Q14749
• Background: The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).
• Synonyms: glycine N-methyltransferase; OTTHUMP00000016412

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycine, serine and threonine metabolism