NIT1 Mouse Monoclonal Antibody [Clone ID: OTI4D12]
Anti-NIT1 mouse monoclonal antibody, clone OTI4D12 (formerly 4D12)
Product Datasheet for 'TA501034'
|Applications||FC, IF, IHC, WB|
|Recommend Dilution||WB 1:1000, IHC 1:50, IF 1:100, Flow 1:100|
|Immunogen||Full length human recombinant protein of human NIT1 (NP_005591) produced in HEK293T cell.|
|Formulation||PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purification||Purified from mouse ascites fluids by affinity chromatography|
|Predicted Protein Size||35.7 kDa|
|Gene Name||nitrilase 1|
|Background||Play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.|
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