Neurogenin3 (NEUROG3) Mouse Monoclonal Antibody [Clone ID: OTI5A8]

SKU TA500090S

Anti-Ngn3 (Neurogenin3) mouse monoclonal antibody, clone OTI5A8 (formerly 5A8)

Product Data

• Clone Name: OTI5A8
• Application: IHC, IP
• Recommended Dilution: IHC: 1:150
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant fragment expressed in E.coli corresponding to amino acids 1-214of human Ngn3
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 22.9 kDa
• Gene Name: neurogenin 3
• Database Link:
  NP_066279
  Q9Y4Z2
• Background: Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm (Gradwohl et al., 2000 [PubMed 10677506]).[
• Synonyms: Atoh5; bHLHa7; Math4B; NGN-3; ngn3

Reference Data

• Protein Families: ES Cell Differentiation/IPS
• Protein Pathways: Maturity onset diabetes of the young