Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2E4]
CAT#: TA500022AM
CK8 (Keratin 8) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4), Biotinylated
Conjugation: Unconjugated HRP
USD 436.00
Specifications
Product Data | |
Clone Name | OTI2E4 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:500~1000, IHC 1:50, IF 1:50~100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 53.5 kDa |
Gene Name | keratin 8 |
Database Link | |
Background | Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
Synonyms | CARD2; CK-8; CK8; CYK8; K2C8; K8; KO |
Reference Data | |
Protein Families | Druggable Genome |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF500022 | Carrier-free (BSA/glycerol-free) CK8 mouse monoclonal antibody, clone OTI2E4 (formerly 2E4) |
USD 600.00 |
|
TA500022 | CK8 (Keratin 8) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4) |
USD 447.00 |
|
TA500022BM | CK8 (Keratin 8) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4), HRP conjugated |
USD 509.00 |
|
TA500022S | CK8 (Keratin 8) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4) |
USD 200.00 |
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