Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: OTI2E4]
Specifications
| Product Data | |
| Clone Name | OTI2E4 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:500~1000, IHC 1:50, IF 1:50~100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 53.5 kDa |
| Gene Name | keratin 8 |
| Database Link | |
| Background | Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
| Synonyms | CARD2; CK-8; CK8; CYK8; K2C8; K8; KO |
| Reference Data | |
| Protein Families | Druggable Genome |
Reviews
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Resources
Other "OTI2E4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA500022 | CK8 (Keratin 8) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4) | 100 ul |
$447.00
|
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| TA500022AM | CK8 (Keratin 8) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4), Biotinylated | 100 ul |
$509.00
|
|
| TA500022BM | CK8 (Keratin 8) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4), HRP conjugated | 100 ul |
$509.00
|
|
| TA500022S | CK8 (Keratin 8) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4) | 30 ul |
$200.00
|
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