Artemin (ARTN) Rabbit Polyclonal Antibody

SKU TA358572

ARTN Antibody - middle region

Product Data

• Application: WB
• Reactivity: Human
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human; Homology: Human: 100%
• Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.; Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 19kDa
• Gene Name: artemin
• Database Link:
  NP_476431
  Q5T4W7
• Background: The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: artemin; ENOVIN; EVN; NBN; neublastin

Reference Data

• Protein Families: Druggable Genome, Secreted Protein