RIZ1 (PRDM2) Rabbit Polyclonal Antibody

SKU TA351337

Rabbit Polyclonal Anti-PRDM2 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA: 1000-2000, WB: 200-1000, IHC: 50-200
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PRDM2
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 189 kDa
• Gene Name: PR domain 2
• Database Link:
  NP_056950
  Q13029
• Background: This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: HUMHOXY1; KMT8; MTB-ZF; RIZ; RIZ1; RIZ2

Reference Data

• Protein Families: Druggable Genome