LOX 1 (OLR1) Rabbit Polyclonal Antibody

SKU TA350815

Rabbit Polyclonal Anti-OLR1 Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 25-100; Positive control: Human thyroid cancer; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human OLR1
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: oxidized low density lipoprotein receptor 1
• Database Link:
  NP_002534
  P78380
• Background: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
• Synonyms: CLEC8A; LOX1; LOXIN; SCARE1; SLOX1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: PPAR signaling pathway