LXN Rabbit Polyclonal Antibody

SKU TA349384

Rabbit Polyclonal Anti-LXN Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1000-5000; WB positive control: A549 cells; IHC: 25-100; Positive control: Human thyroid cancer; Predicted cell location: Cytoplasm and Nucleus
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human LXN
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 26 kDa
• Gene Name: latexin
• Database Link:
  NP_064554
  Q9BS40
• Background: Latexin, also designated endogenous carboxypeptidase inhibitor (ECI) or tissue carboxypeptidase inhibitor (TCI), belongs to the protease inhibitor I47 family of proteins. Latexin acts as a non-competitive, reversible inhibitor for metallocarboxypeptidases (MCPs), including CPA1, CPA2 and CPA4. It is a cytoplasmic protein that is highly expressed in heart, prostate, pancreas, ovary, kidney, brain and colon. Latexin consists of two topologically equivalent subdomains that bind to MCPs with low specificity, which gives it with the flexibility to inhibit all vertebrate A/B MCPs.
• Synonyms: ECI; TCI

Reference Data