RUNX1T1 Rabbit Polyclonal Antibody

SKU TA347281

Rabbit Polyclonal AML-ETO Antibody

Product Data

• Application: ELISA, WB
• Recommended Dilution: ELISA (1:100); Western blotting (1:1,000)
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-AML-ETO antibody: the AML-ETO (RUNX1) fusion protein, using 3 different KLH-conjugated synthetic peptides. The antibody recognizes the ETO (RUNX1T1) part of the fusion protein.
• Concentration: lot specific
• Purification: Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: RUNX1 translocation partner 1
• Database Link:
  NP_783553
  Q06455
• Background: RUNX1T1 (UniProt/Swiss-Prot entry Q06455) is a putative transcription factor which forms a heterodimer with CBFA2T3. Defects in RUNX1T1 have been associated with acute myeloid leukemia (AML-M2) and may be a cause of colorectal cancer.
• Synonyms: AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Pathways in cancer