FOXP1 Mouse Monoclonal Antibody [Clone ID: JC12]

SKU TA336483

Mouse Monoclonal FoxP1 Antibody (JC12)

Product Data

• Clone Name: JC12
• Application: CyTOF-ready, FC, ICC/IF, IHC, IP, WB
• Recommended Dilution: Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin: 1:200-1:500, Immunohistochemistry-Frozen: 1:10-1:500, Flow Cytometry: 1 ug per million cells, Immunohistochemistry: 1:10-1:500, Western Blot: 2ug/ml, CyTOF-ready
• Reactivity: Human, Mouse
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human FOXP1 [Uniprot# Q9H334]
• Buffer: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: forkhead box P1
• Database Link:
  NP_116071
  Q9H334
• Background: FOXP1 is a member of the Forkhead Box Protein family. These proteins are transcription factors that are characterised by a highly conserved forkhead DNA-binding domain. FOXP1 is a repressor of transcription. It forms homodimers, and also heterodimerises with FOXP2 and FOXP4, to facilitate its binding to DNA for transcriptional regulation. A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukaemia, and FOXP1 is also implicated in mental retardation with language impairment and autistic features (MRLIAF). Chromosomal translocation of FOXP1 is implicated in mucosa-associated lymphoid tissue (MALT) lymphoma.
• Synonyms: 12CC4; hFKH1B; HSPC215; MFH; QRF1
• Note: Heat induced antigen retrieval with Sodium Citrate buffer pH 6.0 is recommended when using this antibody for IHC-P.

Reference Data

• Protein Families: Transcription Factors