alpha smooth muscle Actin (ACTA2) Mouse Monoclonal Antibody [Clone ID: 1A4]

SKU TA327604

Mouse Monoclonal Actin, Smooth Muscle Antibody

Product Data

• Clone Name: 1A4
• Application: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Buffer: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: actin, alpha 2, smooth muscle, aorta
• Database Link:
  NP_001604
  P62736
• Synonyms: AAT6; ACTSA; MYMY5
• Note: Actin is a major component of the cytoskeleton and is present in most cell types. Anti-smooth muscle actin does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin is positive. Leiomyosarcomas are positive with both anti-muscle specific actin and anti-smooth muscle actin.

Reference Data

• Protein Pathways: Vascular smooth muscle contraction