PRKAR1B Rabbit Polyclonal Antibody

SKU TA323986

Anti-PRKAR1B rabbit polyclonal antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 1000-5000; WB positive control: Human colon cancer tissue; IHC: 50-200; Positive control: Human breast cancer; Predicted cell location: Cytoplasm, Nucleus
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 50-62 amino acids of Human protein kinase, cAMP-dependent, regulatory, type I, beta
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 43 kDa
• Gene Name: protein kinase cAMP-dependent type I regulatory subunit beta
• Database Link:
  NP_001158230
  P31321
• Background: Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.
• Synonyms: PRKAR1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis, Insulin signaling pathway