Cathelicidin (CAMP) Rabbit Polyclonal Antibody

SKU TA306515

Rabbit Polyclonal Cathelicidin Antibody

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Cathelicidin antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human Cathelicidin.
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: lot specific
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Antibody can be stored at 4°C up to one year.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: cathelicidin antimicrobial peptide
• Database Link:
  NP_004336
  P49913
• Background: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
• Synonyms: CAP-18; CAP18; CRAMP; FALL-39; FALL39; HSD26; LL37

Reference Data

• Protein Families: Secreted Protein, Transmembrane