Oct4 (POU5F1) Rabbit Polyclonal Antibody

SKU TA301457

Rabbit Polyclonal Antibody against OCT4 - Embryonic Stem Cell Marker

Product Data

• Application: FC, ICC/IF, IHC, WB
• Recommended Dilution: Flow Cytometry: 1:50-1:200, Immunocytochemistry/ Immunofluorescence: 1:50-1:200, Western Blot, Immunohistochemistry-Paraffin: 1:200
• Reactivity: Human, Monkey
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to an internal portion of the human OCT4 protein sequence (between residues 100-200).
• Buffer: Tris-glycine, 150mM NaCl and 0.05% sodium azide
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: POU class 5 homeobox 1
• Database Link:
  NP_002692
  Q01860
• Background: Stem cells are crucial ingredients in the progressive restriction of cellular developmental capacity during mammalian embryogenesis. Until recently, only embryonic stem cells (ESC) had been shown to exhibit the potential to differentiate into cells of the all three germ layers. However, adult stem cells (ASC) can regain pluripotency (potential to differentiate into various lineages) if transferred from one stem-cell microenvironment into another. The transcription factor OCT4, expressed in ESCs and germ cells, is strongly implicated in the process of maintaining as well as regaining stem-cell pluripotency and functions as a key regulator of mammalian germline development.
• Synonyms: Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors