CD42a (GP9) Mouse Monoclonal Antibody [Clone ID: GRP-P]

SKU SM1104PS

CD42a (GP9) mouse monoclonal antibody, clone GRP-P, Purified

Product Data

• Clone Name: GRP-P
• Application: FC
• Recommended Dilution: Flow Cytometry.
• Reactivity: Canine, Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human acute lymphoblastic leukemia cells
• Specificity: The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets. HLDA IV.; WS Code P 35.
• Buffer: PBS, pH~7.4; State: Purified; State: Liquid purified IgG fraction from cell Culture Supernatant (> 95% pure by SDS-PAGE); Preservative: 15 mM Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein-A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.; DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: glycoprotein IX platelet
• Database Link:
  P14770
• Background: CD42a, also known as Glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
• Synonyms: Platelet glycoprotein IX, GP-IX, GP9

Reference Data