Hepatitis B Surface Antigen / HBsAg (ad/ay) Goat Polyclonal Antibody
Product Data | |
Application | ELISA, Ie, WB |
---|---|
Recommended Dilution | Suitable for avidin and streptavidin amplifications systems for IEP and ELISA (starting dilution 1/1000). Western Blot. |
Reactivity | Hepatitis B Virus |
Antibody Host | Goat |
Clonality | Polyclonal |
Immunogen | Mixture of subtypes ad & ay. Hepatitis B surface antigen purified from human serum. |
Specificity | Purified Hepatitis B surface antigen. Non-reactive with normal human serum. Monospecific, reacts only with Hepatitis B virus. |
Buffer | 0.01 M PBS, pH 7.2 with 0.09% sodium azide as preservative. No stabilizing proteins have been added. Label: Biotin State: Liquid purified Ig fraction. Label: Covalently coupled with the N-Hydroxysuccinimide ester of under mild conditions to give a high degree of substitution |
Concentration | lot specific |
Conjugation | Biotin |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Background | Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. |
Synonyms | HBV surface antigen, Hepatitis B Virus |
Reference Data |
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