Hepatitis B Surface Antigen / HBsAg (ad/ay) Goat Polyclonal Antibody

SKU BP1028

Hepatitis B Surface Antigen / HBsAg (ad/ay) goat polyclonal antibody, Purified

Product Data

• Application: ELISA
• Recommended Dilution: ELISA: 1/1000.; Though not tested this antibody is likely suitable for immunohistochemistry, fluorescence microscopy, Western Blot and conjugation.
• Reactivity: Hepatitis B Virus
• Antibody Host: Goat
• Clonality: Polyclonal
• Immunogen: Hepatitis B Surface Antigen purified from Human serum. Mixture of subtypes ad and ay.
• Specificity: The antibody is monospecific to purified surface antigen HBsAg.
• Buffer: 0.01 M PBS, pH 7.2, with 0.09% Sodium Azide as preservative without stabilizing proteins.; State: Purified; State: Liquid purified Ig fraction (> 95% pure) .
• Concentration: lot specific
• Purification: Sodium Sulfate Precipitation and ion Exchange Chromatography.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Background: Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
• Synonyms: HBV surface antigen, Hepatitis B Virus

Reference Data