CD300 antigen (CD300A) Mouse Monoclonal Antibody [Clone ID: MEM-260]
$440.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | MEM-260 |
|---|---|
| Application | FC |
| Recommended Dilution | Suitable for Flow Cytometry analysis of Human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | HPB Human acute lymphoid leukemia cell line |
| Specificity | The antibody reacts with CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25% of circulating T cells and 15% of circulating B cells. |
| Buffer | Phosphate buffered saline (PBS) solution containing 15mM sodium azide Label: PE State: Liquid purified IgG fraction Label: Conjugated with R-Phycoerythrin under optimum conditions |
| Purification | Size-Exclusion Chromatography |
| Conjugation | PE |
| Storage | Store the antibody in the dark at 2-8°C. DO NOT FREEZE! Avoid prolonged exposure to light. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD300a molecule |
| Database Link | |
| Background | CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity. |
| Synonyms | CLM-8, CMRF35-H, CMRF35-H9, CMRF-35-H9, IRC1/IRC2, IRp60 |
| Reference Data | |
| Atlas Protein Categories | CD Markers, Intracellular Proteins, Membrane Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.