HLA Class I ABC Mouse Monoclonal Antibody [Clone ID: W6/32]

SKU AM03005FC-N

HLA Class I ABC mouse monoclonal antibody, clone W6/32, FITC

Product Data

• Clone Name: W6/32
• Application: FC
• Recommended Dilution: Flow Cytometry (1/300 as starting dilution).
• Reactivity: Bovine, Feline, Human, Primate
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Membrane of Human tonsil cells
• Specificity: The antibody W6/32 recognizes virtually all nucleated human cells. It is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders.; This antibody W6/32 is also suitable as a Positive Control for HLA tissue typing and crossmatching.
• Buffer: Phosphate buffered saline (PBS), pH~7.4; Label: FITC; State: Liquid purified IgG fraction; Preservative: 15 mM Sodium Azide; Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC.
• Concentration: lot specific
• Conjugation: FITC
• Storage: Store the antibody undiluted at 2-8°C.; DO NOT FREEZE!; This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Background: HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta-2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.; MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types.
• Synonyms: MHC class I ABC, HLA Class 2 ABC

Reference Data